We present our 10-year experience of SPM in patients with GIST from a regional Cancer Centre in Canada.Methods:A retrospective cohort study was performed in all GIST patients treated at TOH between January 2011 and December 2021. Patients were identified using ICD-10 codes and electronic medical...
Evaluation of esophageal masses and for directing biopsies for diagnosing esophageal cancer; Evaluation of persons with signs or symptoms of loco-regional recurrence after resection of esophageal cancer; Evaluation of persistent vomiting of unknown cause; Evaluation of other diseases in which the presence ...
The epithelial cells of the gastrointestinal (GI) tract communicate with each other and with cells of other organs via a complex network of highly regulated movement of ions and biomolecules. The molecules ensure regulated activity of cells, tissues, and
Gastrointestinal stromal tumors (GISTs) are a rare type of tumor that can develop liver metastasis (LIM), significantly impacting the patient's prognosis. This study aimed to predict LIM in GIST patients by constructing machine learning (ML) algorithms t
Overexpressing the intracellular domain of NOTCH3 (N3ICD) can up-regulate the expression of Cdh1 and cause p27Kip accumulate by accelerating the degradation of Skp2, as well as inhibit the breast cancer cell line, MDA-MB-231, proliferation and colony formation rate. That’s to say NOTCH3 ...
Each gastrointestinal cancer was analyzed separately based on the International Classification of Diseases for Oncology third edition (ICD-O-3) for the common histologic type. Meanwhile, based on the sequence of cancer occurrence in the patients, they were divided into the one primary (OP) group ...
Banerjee, S.et al.KIT(low) cells mediate imatinib resistance in gastrointestinal stromal tumor.Mol. Cancer Ther.https://doi.org/10.1158/1535-7163.MCT-20-0973 Which is the optimal risk stratification system for surgically treated localized primary GIST? Comparison of three contemporary prognostic crit...
Cancer is a worldwide burden resulting in millions of deaths each year. In particular, gastrointestinal tumors are life-threatening malignancies and one of the leading reasons for death in developed countries. Phytochemicals can be found in grains, vegetables, fruits and several foods. Many phytochemi...