Scientists with the American Society for Microbiology, or ASM, called for standardized practices, greater public transparency and more in a new report on gain-of-function research, studies where microbes are given characteristics that don’t exist in nature and, in some cases, could make them mo...
Policy and public health in microbiology Viral pathogenesis Viral transmission This article is cited by Biosynthesis pathways of expanding carbon chains for producing advanced biofuels Haifeng Su JiaFu Lin Biotechnology for Biofuels and Bioproducts (2023) Gain-of-Function Research: Ethical Analysis Mich...
Recent gain-of-function studies in influenza A virus H5N1 strains revealed that as few as three amino-acid changes in the hemagglutinin protein confer the capacity for viral transmission between ferrets1, 2. As transmission between ferrets is considered a surrogate indicator of transmissibility between...
Researchers have traced and characterized the formation of the early gut microbiome in early infanthood.
Gain-of-Function Alleles Systematic analysis of deletion mutant alleles, both individually and in combination, have made an enormous impact on gene function discovery. However, while loss-of-function genetic analyses identify functionally coherent gene modules and the connections between them, they are ...
Inborn error of ImmunityNF-κB signalingJournal of Clinical Immunology - Biallelic loss-of-function variants in IKBKB cause severe combined immunodeficiency. We describe a case of autoimmunity and autoinflammation in a male infant with a...
We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...
President of the British Medical Association Dear Professor Gillon, why is SARS-CoV-2 such a major problem, given that other coronaviruses are regarded as common colds? Is it possible that ‘gain of function’ research has been undertaken on this virus?
loss-of-function and gain-of-function James Yi-Hsin Chan1,2, Ying-Chuan Chen3, Shu-Ting Liu3, Wei-Yuan Chou3*, Ching-Liang Ho4* and Shih-Ming Huang3* Abstract Background: p53 is a major tumor suppressor that is inactivated in over 50% of human cancer types through either mutation ...
In this paper, a class of variable coefficient coupled Schrdinger equations with gain or loss terms is studied, which can be used to describe soliton excit... X Wang,LL Zhang - 《Nonlinear Dynamics》 被引量: 0发表: 2023年 Gain or loss: A conceptual framework of employee well-being during...