Gain-of-Function Debate A Disputed Testcase for Biosecurity Policy11 August 2015 Koos van der BruggenOverview of presentation1. The gain-of-function concept 2. Highlights of the debate 3. The H5N1 debate in The Netherlands as an exampleWhat is gain-of function research? (1) Gain-of-function...
The debate on whether to allow experiments that increase the transmission and/or pathogenicity of potential pandemic pathogens has recently gained renewed attention, particularly as a result of studies on influenza viruses. Here, five experts discuss the
Still, the debate has sparked renewed calls from scientists to address transparency, communication and biosecurity around gain-of-function research. At the same time, scientists have also warned not to overstate the risks, as studies on organisms with pandemic potential—which fall under a subtype ...
The mystery of COVID’s origins has reignited a contentious debate about potentially risky studies and the fuzzy terminology that describes them.
The Wall Street Journal editorial board accused the media of "groupthink" in avoiding coverage of potential gain-of-function research at the Wuhan Institute of Virology because doing so might give credence to Sen. Rand Paul, R-Ky., and "the populist righ
mBio. Research on Highly Pathogenic H5N1 Influenza Virus: The Way Forward. Anthony S. Fauci. September-October 2012, 3(5): e00359-12. doi: 10.1128/mBio.00359-12 mBio. Falling down the rabbit hole: aTRIP toward lexiconic precision in the “gain-of-function” debate. W...
The survey comes as questions over the origins of the COVID-19 virus has reignited debate over the ethics of the gain of function research.The most recent Hill-HarrisX poll was conducted online among 950 registered voters. It has a margin...
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Growth and innovation in the food and beverage industry is being driven by an increasingly demanding population of Chinese foodies. According to the Beijing-based research firm AskCI Corp., the value of China's food and beverage market is expected to exceed 5 trillion yuan ($742 billion) by ...
p53 is mutated in over half of human cancers. In addition to losing wild-type (WT) tumor-suppressive function, mutant p53 proteins are proposed to acquire gain-of-function (GOF) activity, leading to novel oncogenic phenotypes. To study mutant p53 GOF mec