However, no gender difference in the incidence of type 1 diabetes is found. The frequency of antibodies against glutamic acid decarboxylase (GADA) in diabetes mellitus depends on age at diagnosis and also gender. Several studies have shown that high GADA levels can predict future 尾-cell failure...
GAD属于抑制性神经递质γ-氨基丁酸(gamma-aminobutyric acid,GABA)合成限速酶,GAD抗体在1988年被最早描述,是第一个被确认的突触蛋白抗体,其存在于多种神经系统疾病和1型糖尿病(type 1 diabetes mellitus,T1DM)。随后,越来越多的靶向细胞内和细胞表面蛋白以及...
4、Katsarou A, Gudbjornsdottir S, Rawshani A, et al. Type 1 diabetes mellitus. Nat Rev Dis Primers,2017,3(9):17016. 5、Tuomi,T. et al. Antibodies to glutamic acid decarboxylase reveal latent autoimmune diabetes mellitus in adults with a non...
GAD属于抑制性神经递质γ-氨基丁酸(gamma-aminobutyric acid,GABA)合成限速酶,GAD抗体在1988年被最早描述,是第一个被确认的突触蛋白抗体,其存在于多种神经系统疾病和1型糖尿病(type 1 diabetes mellitus,T1DM)。随后,越来越多的靶向细胞内和细胞表面蛋白以及兴奋性和抑制性突触受体的抗体被确定为中枢神经系统(central ...
Antibodies to glutamic acid decarboxylase and insulin-dependent diabetes in patients with auto-immune polyendocrine syndrome type I J Clin Endocrinol Metab (1996) A. Saiz et al. Autoantibodies to glutamic acid decarboxylase in three patients with cerebellar ataxia, late-onset insulin-dependent diabetes...
Iconography : Auto-immune cerebellar ataxia with anti-GAD antibodies accompanied by de novo late-onset type 1 diabetes mellitus Diabetes & Metabolism - Vol. 34 - N° 4 - p. 386-388 - Iconography : Auto-immune cerebellar ataxia with anti-GAD antibodies accompanied by de novo late-ons... C...
Antibodies to glutamic acid decarboxylase-65 (GAD65) are present in autoimmune disorders such as insulin-dependent (type1) diabetes mellitus (IDDM), stiff man syndrome, and polyendocrine autoimmune disease. Autoantibodies to GAD65 are present in 60-70% of individuals with newly diagnosed IDDM, and...
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Islet cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies Lancet (1974) D.B Jones et al. Heat-shock protein 65 as a B-cell antigen of insulin-dependent diabetes Lancet (1990) M Pietropaolo et al. Combined analysis of GAD65 and ICA512(IA-2) autoantibodies in organ...
During the admission period, he was found to have anti-GAD and JA-2 antibodies indicating that he was suffered from type 1 diabetes. We report this case because the occurence of type 1 diabetes with ITP is considered to be relatively rare....