WORKSHOP A: STRUCTURE AND FUNCTION OF MHC CLASS I AND CLASS IV MOLECULESFirst page of articledoi:10.1111/j.1744-313X.1987.tb00355.xG. B. FerraraJ. C. HowardJohn Wiley & Sons, Ltd (10.1111)International Journal of Immunogenetics
Antigen presentation by major histocompatibility complex class I (MHC-I) and class II (MHC-II) molecules is a prerequisite for T cell engagement during the activation as well as the effector phase. The central nervous system (CNS) is unique in that cells resident in the parenchyma, glia and...
MHC class I modulates NMDA receptor function and AMPA receptor trafficking. Proc Natl Acad Sci U S A. 2010;107(51):22278-83.Fourgeaud L, Davenport ... Fourgeaud,Davenport,M C.,... 被引量: 0发表: 0年 Clathrin adaptor AP2 and NSF interact with overlapping sites of GluR2 and play disti...
The addition of MHC-class I monoclonal antibody (mAb) in combination with CD16 mAb resulted in a significant potentiation of the inhibition of NK cell cytotoxic function and both accelerated kinetics and synergistic induction of cell death in both resting and IL-2-treated human peripheral blood ...
The surface presentation of peptides by major histocompatibility complex (MHC) class I molecules is critical to all CD8+ T-cell adaptive immune responses, including those against tumors. The generation of peptides and their loading on MHC class I molecules is a multistep process involving multiple...
Whether B cells serve as antigen-presenting cells (APCs) for activation of pathogenic T cells in the multiple sclerosis model experimental autoimmune encephalomyelitis (EAE) is unclear. To evaluate their role as APCs, we engineered mice selectively deficient in MHC II on B cells (B-MHC II-/-)...
Human MHC Class II Antigens: Genetics, Structure and Function Proceedings of the First International Workshop on Monoclonal Antibodies to Human MHC Class II Antigens Disease Markers (special issue) — Volume 2: Edited by H.M. Dick, C.M. Steel and B. Dupont John Wiley and Sons, Chichester...
Vaccination with Ep-CAM protein or anti-idiotypic antibody induces Th1-biased response against MHC class I- and II-restricted Ep-CAM epitopes in colorectal carcinoma patients Clin. Cancer Res., 10 (2004), pp. 5391-5402 View in ScopusGoogle Scholar [137] E. Bremer, D. Samplonius, B.-J...
By using an MHC deficient cell line, we have shown that HCV core35-44 peptide is capable of enhancing cell surface expression of MHC class I (HLA-C and HLA-E). Although this peptide stabilises HLA-E, the HLA-E:HCV core35-44 complex alone is insufficient to inhibit at NKG2A positive ...
Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 1994; 368: 215–21. PubMed CAS Google Scholar Falk K, Rötzschke O, Stevanovié S et al. Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide ...