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class I and class II MHC molecules.To test this theory, we inserted the human tumor antigen gp100 into mouse DCs transgenic for HLA-DRb1 * 0401 using either adenoviral vector or a VSV-G pseudotyped retroviral vector. DCstransduced with tumor antigen were able to be recognized by both a ...
MHC molecules are polymorphic, and the biology of the various alleles differs, such that they can potentially have different consequences with regards to the relevant immune responses. This point is best-defined for MHC class I molecules. In this Review, we bring this into context with the curre...
Yeager M,Carrington M,Hughes AL.Class I and class II MHC bind self peptide sets that are strikingly different in their evolutionary characteristics. Immunogenetics . 2000Yeager, M., M. Carrington, and A. L. Hughes. 2000. Class I and class II MHC bind self peptide sets that are strikingly...
MHC class I, MHC class II and intercellular adhesion molecule-1 (ICAM-1) expression in inflammatory myopathies. We investigated the relationship between the MHC-I, MHC-II and intercellular adhesion molecule-1 (ICAM-1) expression on myofibres and the presence of infla... E Bartoccioni,S Gal...
The expression of MHC class II antigens and ICAM-1 and the composition of lymphocyte infiltrates have been studied in frozen sections of transbronchial biopsies from lung transplant recipients. First, biopsies obtained from patients who showed acute rejection, OB, and normal features were compared. ...
developmentandexecutionofimmuneresponses 7 Histocompatibility Genes Manygenesareinvolved,>30namedlociinmiceOnegroupoflinkedgenespredominatesinevery vertebratespecies:MajorHistocompatibilityComplex,“MHC”Mouse–“H-2”Human–“HLA”编码主要组织相容性抗原的一组紧密连锁的基因群,主要功能是以其产物向T细胞...
The major histocompatibility complex (MHC) has a central role in the specific immune defence of vertebrates. Exon 3 of MHC class I genes encodes the domain that binds and presents peptides from pathogens that trigger immune reactions. Here we develop a f
Products Intro:Product Name:MHC Class I H-2Dd antibody [D1] CB Index:58 Related Information:Catalog(6025) Company Name: Beijing Bai Ao Si Biotechnology Co., Ltd. Tel:010-60291560 Products Intro:Product Name:MHC Class I H-2Dd antibody [D1] CB Index:58 Related Information:Catalog(699...
Description: The 34-1-2S monoclonal antibody reacts with the mouse MHC class I, H-2Kd and H-2Dd. This cytotoxic antibody also cross-reacts with Kb, s, r, q, p.Applications Reported: 34-1-2S has been reported for use in flow cytometric analysis.Applications Tested: T...