Home Services Fullgen offers whole exome sequencing (WES) as well as whole genome sequencing (WGS).This sequencing technology looks at all the coding regions of a person’s genome, examining thousands of genes simultaneously. For this reason, WES and WGS are among the best methods of detecti...
Our Services Whole Exome Sequencing The sum of all coding regions in a genome is called the exome. In humans, this includes 23,000 genes with… Read More > Whole Genome Sequencing Whole Genome Sequencing (WGS) provides the most comprehensive map of an organism’s genetic make-up… ...
The human genome project was a ground-breaking scientific endeavour that not only gave us a near complete map of our genetic code but also paved the way for new innovative sequencing technologies and computational methods that have enabled the clinical application of genomics [1,2,3,4]. While ...
Annotation of variants from next-generation sequencing data using a reference genome RVIS: Residual variation intolerance score LoFtool: Loss of function tool DS: Delta score AG: Acceptor gain AL: Acceptor loss DG: Donor gain DL: Donor loss DP: Delta position AF: Allele frequency ...
genome-wide cytogenetic and molecular genomic testing approaches (karyotyping, chromosomal microarray [CMA], exome sequencing [ES]) has driven much of the rare disease discovery to this point, with genome sequencing representing the newest member of this team. Each step has brought increased sensitivi...
Lack of functional evidence hampers variant interpretation, leaving a large proportion of individuals with a suspected Mendelian disorder without genetic diagnosis after whole genome or whole exome sequencing (WES). Research studies advocate to further s
Library construction and genome sequencing The genomic DNA ofT. mongolicuswas extracted from the leaves using a modified CTAB method [34]. Quality of the isolated DNA was assessed using NanoDrop-2000 (Thermo Fisher Scientific, Wilmington, DE, USA) and Qubit 3.0 fluorometer (Life Technologies). The...
The whole genome of SH-SY5Y cell line was re-sequenced using two different sequencing platforms, those from Complete Genomics (CG) and Illumina (IL) HiSeq2000, to generate a high-quality list of variants. An earlier study has shown the utility of combining information from both platforms and...
Whole-genome sequencing of giant pandas provides insights into demographic history and local adaptation. Nat. Genet. 45, 67–71 (2013). Article CAS PubMed Google Scholar Duke, N. C. in Mangrove Ecosystems: A Global Biogeographic Perspective (eds Rivera-Monroy, V. H. et al.) 17–53 (...
In this review, we describe the emerging single-cell sequencing technique and its application in atherosclerosis. These technologies have the potential to facilitate a deeper analysis of atherosclerosis, translate the data into clinical applications, and provide improved precision medical services for ...