Institutional review boards at University of Delaware, Ahmadu Bello University and the Imo State Federal Medical Center approved the IRB application involving this study, the research protocol, and the form for informed consent. Consent for publication All authors consented to the publication of this ...
action potential duration at 90% of repolarization (panel d, APD90 20 ms: 287.4 ± 19.6 ms, n = 30; APD90 200 ms: 402 ± 19 ms, n = 24), maximum diastolic potential (panel e, MDP 20 ms: -83.7 ± 0.9 mV, n = 23; MDP 200 ms: -84.88 ...
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The AI-based algorithm of the platform is based on the reinforcement learning. This algorithm is formalized through a Markov’s decision-making process (MDP) (S, A, p, r). The state transition function p: S× A× S→ [0, ∞) gives the distribution of the next state, St+1 based on...
During the production MD steps, we removed the positional restraints to observe the natural dynamics of the proteins and ligand-bound complexes. The molecular dynamics parameters (MDP) files were adjusted for the ligand-bound MurM systems during energy minimization, NVT equilibration, NPT equilibration...
n = 32–60 cells from at least 3 independent batches of differentiation. E, F Representative spontaneous AP tracings of KD control, TRPA1 KD, OE control, and TRPA1 OE mESC-CMs. G, H Bar graphs showing the DDR, Vmax-upstroke, MDP, and amplitude of APs. n = 11–26 cells...
Policy Testing with MDPFuzz (Replicability Study) (2024). In Proceedings of the 33rd ACM SIGSOFT International Symposium on Software Testing and Analysis published by Association for Computing Machinery [PDF] [bib][DOI] Distinguished Paper Award Abstract Olivier Zeyen, Maxime Cordy, Gilles Perrouin,...
XX flexibility: Current evidence suggests that X inactivation is not fully paternally imprinted in human placenta, instead exhibiting a form of large-scale clonal mosaicism with a slight bias towards maternal X expression (54, 56). In addition to random and/or clonally skewed XX mosaicism acting ...
1 . specifically, most existing work schedules tasks in batch form, while gd-drl is able to schedule real-time tasks using double deep q-network (ddqn). we have applied ddqn to the task characteristics generated by the digital twin technology of the power grid, which is a novel ...
The active mature form, mGDF15, is released via the proteolytic cleavage of dimeric pro-GDF15 at a furin-like site (RXXR) [21,22,23]. A recent study showed that mGDF15 binds to glial cell-derived neurotrophic factor family receptor alpha-like, is involved in PI3K/Akt/mTOR pathway ...