Full size image MDP pretreatment augments IFN-β response during HCMV infection Since MDP pretreatment inhibited HCMV replication (Fig. 4) and its addition after infection induced the phosphorylation of TBK, IRF3 and IFN-β expression (Fig. 2C,E,F), we hypothesized that the antiviral effects ...
A full MS scan (350–1,600 m/z range) was acquired at a resolution of 70,000 at an m/z of 200 and a maximum ion accumulation time of 100 ms. Dynamic exclusion was set as 30 s. Resolution for HCD spectra was set to 35,000 at an m/z of 200. The AGC setting of full MS ...
View full text Impact of Expression of CD44, a Cancer Stem Cell Marker, on the Treatment Outcomes of Intensity Modulated Radiation Therapy in Patients With Oropharyngeal Squamous Cell Carcinoma International Journal of Radiation Oncology*Biology*Physics, Volume 94, Issue 3, 2016, pp. 461-468 ...
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Full size image As E3 ligases attach ubiquitin chains to the lysine residues of target proteins, we aimed to identify the lysines on RIP2 that are potentially involved in its regulation by ZNRF4. Since the CARD domain of RIP2 alone was sufficient for degradation, we reasoned that the lysine...