The proteins selected for fusions with CBD were highly reengineered, or ‘artificial’ (= not existing in Nature), which carried condensed functionalisation in the form of concatemers. These were composed of repetitive, bioactive epitopes, oriented in organised head-to-tail fashion, expressed ...
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We exposed retinal explants to Treg secretome in the presence or absence of a pro-inflammatory stimulus in the form of lipopolysaccharide (LPS) and investigated cone survival by staining for CA. LPS is a widely used pro-inflammatory activator of microglia and macrophages [33], which at least ...
Particularly, arterial hiPSC-ECs can form a more extensive capillary network in vivo [28]. In general, though hiPSC-ECs provide a novel notion, their scientific and therapeutic potential still remain to be carefully assessed in clinical application (Figure 6). Figure 6 Induced pluripotent stem ...
Genetically susceptible individuals form anti-citrullinated protein antibodies (ACPAs) as part of a loss of tolerance to citrullinated and other posttranslationally modified proteins. As inflammation increases secondary to the loss of tolerance, the levels of inflammatory cytokines such as tumor necrosis ...
2 show census totals that do not adjust for observer error, mainly in the form of undercounting small or obscured plants, because all censuses prior to the most recent one did not attempt to quantify error rates. Earlier reports acknowledged the considerable uncertainty inherent in the census ...
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the expression matrix is normalized within each cell and log-transformed to further suppress potential extreme values. Feature selection involves any form of expression profile dimension reduction or subsetting steps. Due to the variability in preprocessing steps across different methods, it is challenging...
This process is followed by sexual reproduction to form zygotes, which develop into oocysts [2]. These oocysts are released from the intestinal epithelial cells and excreted with the intestinal contents. Under suitable environmental conditions, the oocysts develop into sporulated oocysts. A new ...
Taking into account medical education theory and design elements from implementation science, the Calgary office of the Alberta Physician Learning Program (CPLP) developed an approach to a novel form of audit and feedback presented within a collegial peer environment. The CPLP develops and delivers au...