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Due to the systemic Treg depletion used in our diphtheria toxin model, it is not possible to determine whether Treg exert a local function within the retina or act indirectly through the maintenance of systemic homeostasis. To build on this and taking into account the enhanced inflammatory and ne...
illustration of the set of methods benchmarked, which includes 16 clustering methods, five alignment methods, and five integration methods. Bottom, overview of the benchmarking analysis, in terms of different metrics (1–7). Different experimental metrics and analyses,...
Taking into account medical education theory and design elements from implementation science, the Calgary office of the Alberta Physician Learning Program (CPLP) developed an approach to a novel form of audit and feedback presented within a collegial peer environment. The CPLP develops and delivers au...
Conjugation methods were used that allowed the drugs to be released in active form inside the cell body after transport. Intramuscular and intradermal injection proved effective for introducing pharmacologically effective doses into selected populations of CNS neurons. Pharmacological efficacy with gabapentin...
Obviously, monitoring the precursor at basic pH and its glycosilated form at acidic pH can be informative as biomarker of disease [27, 28]. Likewise, we identified tryptophan 5-hydroxylase 1 (TPH1_MOUSE) in the serum proteome. This protein promotes the synthesis of 5-HT (serotonin). ...
pallasii demonstrate remarkable heterogeneity of their life histories (e.g. [10]). In the White Sea Gulf of Kandalaksha, a fast-growing summer-spawning form similar to typical Pacific herring is distinguished from a more abundant slow-growing form, which uniquely breeds under the ice in the ...
(with radius measured from a zone of approximately 4.5 cm beyond the pith), and a similar trend was found for stiffness. The relationships, which were incorporated in models to estimate wood properties within individual trees, did not explicitly account for the effects of silvicultural treatments....
We will check whether this relation for θP still fits within the present form of our broken HLS model. As in all previous studies in this series, one could have limited oneself to considering only the η–η mixing, decou- pling this from the π0 sector. However, it is a classical ...
genomes is therefore required to form a functional mitochondrion. Studies of the repertoire of proteins comprising the mitochondrion (mitochondrial proteome or mitoproteome) have revealed that this organelle is a structural and functional amalgam of proteins having different phylogenetic origins: an ...