Define valproic acid. valproic acid synonyms, valproic acid pronunciation, valproic acid translation, English dictionary definition of valproic acid. n. An anticonvulsive drug, C8H15NaO2, given orally and by injection to treat epilepsy. American Heritage
Valproic Acid (VPA) is an important drug for the treatment of several types of seizures because it has a wide spectrum of activity. Since VPA has an unusual nonlinear binding characteristic and a wide interindividual variation, monitoring of its free concentration can be helpful in patient manageme...
Tondi. The free fraction of valproic acid in tears, saliva, and cerebrospinal fluid. Epilepsia 23 :23-26 (1982).F. Monaco, S. Piredda, R. Mutani, C. Mastopaolo, and M. Tondi, "The free fraction of Valproic acid in tears, saliva, and cerebrospinal fluid," Epilepsia. 23, 1982, pp...
Define derepression. derepression synonyms, derepression pronunciation, derepression translation, English dictionary definition of derepression. tr.v. de·re·pressed , de·re·press·ing , de·re·press·es To induce the operation of by deactivating the
In contrast, after treating the cells with X-ray radiation and mitophagy inducers carbonyl cyanide m-chlorophenylhydrazone (CCCP) (Fig. S3F–H) or valproic acid (VPA) (Fig. S3I–K), we observed an increased rate of cell death and reduced clone formation, as well as a considerable rise ...
Several authors have enat]dorsed the routine use of free drug concentration monitoring. Data examining the clinical usefulness of free drug concentration monitoring for phenytoin, carbamazepine, valproic acid, disopyramide and lignocaine (lidocaine) are reviewed. While available evidence suggests that free...
Seizure disorder secondary to brain metastases should be treated with first-line anticonvulsants such as levetiracetam, valproic acid, and/or carbamazepine among others. If the patient is receiving chemotherapy, anticonvulsants that do not induce hepatic cytochrome P450 enzymes should be considered...
Performance of the Quinidine, Lidocaine, Free Phenytoin, and Free Valproic Acid Fp Assays on the Cobas® Integra 400 AnalyzerMotter, K; Bates, M; Honasoge, S; de Flesco, L; Miller, P; Passarelli, J; Salamone, S J Abstract An abstract is unavailable. This article is availa...
Valproic acid: an old drug newly discovered as inhibitor of histone deacetylases. Ann Hematol, 83 (2004), pp. 91-92 Suppl 1 Google Scholar 39 R Reca, D Mastellos, M Majka, et al. Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C...
Valproic acid extends Caenorhabditis elegans lifespan. Aging Cell 2008, 7, 305–317. [Google Scholar] [CrossRef] [PubMed] Zhang, J.; Shi, R.; Li, H.; Xiang, Y.; Xiao, L.; Hu, M.; Ma, F.; Ma, C.W.; Huang, Z. Antioxidant and neuroprotective effects of Dictyophora ...