Elevated free light chain (FLC) concentrations can produce glomerular and tubulointerstitial injuries. We have therefore examined FLC concentrations in patients with chronic kidney disease (CKD) to determine if they may be a causative factor in progressive renal injury. 272 patients were recruited from...
Immunoglobulin crystallization is an uncommon phenomenon that also results in kidney injury. We report the case of a 74-year-old man with recurrent renal colic and acute kidney injury. He presented with kappa light chain Bence-Jones proteinuria, hypogammaglobulinemia, anemia, and high plasma kappa...
Kappa light chain-associated Fanconi's syndrome: molecular analysis of monoclonal immunoglobulin light chains from patients with and without intracellular ... Plasma cell dyscrasias may be responsible for Fanconi's syndrome, due to the toxicity of a free monoclonal kappa light chain toward kidney ...
Free kappa and lambda light chains were assayed by particle-counting immunoassay in cerebrospinal fluid (CSF) from patients with various neurological disorders. Detection limits were 25 and 50 ng/ml, respectively. Values of free kappa chain were higher than 50 ng/ml (upper reference limit) in 15...
上海玉博生物科技有限公司 主要致力于“BF 1011 Kappa Light Chain, Free ”的生产销售。多年的“BF 1011 Kappa Light Chain, Free ”生产与销售的经验,与各行业新老用户建立了稳定的合作关系,我公司经营的产品名称深受广大用户信赖。欢迎来电咨询或前来选购
Free Light Chains (FLCs) are immunoglobulin light chains which are circulating in serum in a free state (unbound). There are two types of immunoglobulin light chain produced in humans, designated kappa (κ) and lambda (λ). The quantification of serum FLC is used as an aid in the diagnosi...
GLBF-80A - anti-Human Bound + Free Lambda Light Chain Polyclonal Antibody Storage 2-8°C Recertification 18 months Molecular Weight ~23,000 Synonyms Bence Jones Protein-Kappa, FLC-Kappa, KLC, KFLCApplications Immunoassay / Immunology Overview Lee Biosolutions is the leading supplier of human ...
Renal impairment (RI) is common in multiple myeloma (MM) and is associated with poor survival. This study reports the associations between renal function and disease characteristics including serum free light chain (FLC) level at diagnosis in patients with MM. Methods Using data from the Medical ...
While investigating 2592 patients enrolled in multicenter myeloma trials, we found light chain-only (LCO) patients had worse median survival times (1.9 years) than patients with IgA and IgG paraproteins (2.3 and 2.5 years, respectively) (P < .001). However, IgA and IgG patients with levels ...
Diazyme Human Kappa Free Light Chain Assay; Diazyme Human Lambda Free Light Chain Assay产品名称,K181438申请号,510k申请类型,Diazyme Laboratories Inc.申请人,数据来源于药智数据美国上市器械数据库。