Foxp3+ regulatory T cells: differentiation, specification, subphenotypes. Nat Immunol. 2009 Jul;10(7):689-95. doi: 10.1038/ni.1760. PMID: 19536194. [4]Kanamori M, Nakatsukasa H, Okada M, Lu Q, Yoshimura A. Induced Regulatory T Cells: Their Development, Stability, and Applications. ...
Peter Georgiev et al, Regulatory T Cells: the Many Faces of Foxp3, Journal of Clinical Immunology,https://doi.org/10.1007/s10875-019-00684-7 Charbonnier LM, Cui Y, Stephen-Victor E, Harb H, Lopez D, Bleesing JJ, et al. Functional reprogramming of regulatory T cells in the absence of...
Whiteside SK et al. Acquisition of suppressive function by conventional T cells limits antitumor immunity upon Treg depletion. Sci Immunol. 2023 Dec 15;8(90):eabo5558.
如果想要进一步了解Treg的功能鉴定方法,一定要持续关注君莲数据库哦~ [1] F. Shan, A. Somasundaram, T.C. Bruno, C.J. Workman, D.A.A. Vignali, Therapeutic targeting of regulatory T cells in cancer, Trends Cancer 8(11) (2022) 944-961. [2]https://www.takarabiomed.com.cn/DownLoad/9767.p...
2021年7月15日，来自美国洛克菲勒大学的Gabriel D. Victora团队在Science上在线发表题为“Expression of Foxp3 by T follicular helper cells in end-stage germinal centers”的文章，发现除了典型的TFR细胞外，还存在着第二群Foxp3 GC T细胞，它们在GC收缩前出现，通过上调Foxp3和TFH细胞有限地获得Treg样特征，证明...
[1] F. Shan, A. Somasundaram, T.C. Bruno, C.J. Workman, D.A.A. Vignali, Therapeutic targeting of regulatory T cells in cancer, Trends Cancer 8(11) (2022) 944-961. [2]https://www.takarabiomed.com.cn/DownLoad/9767.pdf [3]...
Foxp3 转录因子流式固定破膜缓冲液经过配方设计和优化,可使用抗体对转录因子和核蛋白(例如 Foxp3 和 Ki-67)以及细胞因子和趋化因子进行染色。为了您的便利,我们已经提供了这些方案,用于在流式细胞仪上制备细胞内抗原检测用样品。已报告应用细胞内染色,然后进行流式细胞术分析了解更多信息 ...
FoxP3+ cells: Tumor infiltration pattern.Cecilia, HermansDavid, AnzJutta, EngelThomas, KirchnerStefan, EndresDoris, Mayr
FOXP3 is a transcription factor that is essential for the development of regulatory T cells, a branch of T cells that suppress excessive inflammation and autoimmunity1,2,3,4,5. However, the molecular mechanisms of FOXP3 remain unclear. Here we here show that FOXP3 uses the forkhead domain—...
(immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome. Transcript variants of FOXP3 encoding different isoforms have been identified. In human breast and colon cancer cells, expression of FOXP3 is regulated...