Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the in- tervertebral discs. Proc Natl Acad Sci U S A 2011;108:9484-9.Choi KS, Harfe BD. Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei ...
Red blood cells arise continuously from pluripotent stem cells which mature and become functionally specialized upon commitment to the erythroid lineage. I... U Klingmüller - 《European Journal of Biochemistry》 被引量: 288发表: 1997年 Expression of zebrafish connexin43.4 in the notochord and tail...
Chondroitin sulfates have been implicated in the promotion and in the inhibition of axon growth. In the zebrafish embryo, chondroitin sulfates are present at the interface of the somites and the notochord where spinal motor axons extend ventrally to establish the midsegmental ventral motor nerves. ...
Chronic low back pain can be associated with the pathological ingrowth of blood vessels and nerves into intervertebral discs (IVDs). The notochord patterns the IVD during development and is a source of anti-angiogenic soluble factors such as Noggin and Chondroitin sulfate (CS). These factors may ...
Between paired epithelial somites, we sometimes observed a line of cells (Supplementary Fig. 7a). However, those cells did not display any continuous structure that resembles a neural tube or notochord. Some cells at the center were BRACHYURY and SOX2 double-positive (Supplementary Fig. 7b; Suppl...
et al. Segmentation of the zebrafish axial skeleton relies on notochord sheath cells and not on the segmentation clock. eLife 7, e33843 (2018). Article Google Scholar Becskei, A., Kaufmann, B. B. & van Oudenaarden, A. Contributions of low molecule number and chromosomal positioning to ...
Intronic enhancers control expression of zebrafish sonic hedgehog in floor plate and notochord The signalling molecule Sonic hedgehog (Shh) controls a wide range of differentiation processes during vertebrate development. Numerous studies have sugges... F Muller,B.-E. Chang,S Albert,... - 《Develop...
Its expression persists in axial structures derived from the mouse equivalent of Hensen's node, namely definitive endoderm and notochord, and in the ventral region of the developing neural tube. Expression of the highly related gene, HNF3 alpha, appears to initiate later than HNF3 beta and is ...
Further expression was detected in a dorsoventral gradient at the onset of gastrulation and in specific domains in the organizer, notochord and lateral plate mesoderm. Embryos lacking zygotic sur function had variable deficiencies of prechordal plate and ventral neuroectoderm. In the absence of both ...
1. A continuation of the peritoneum that binds the small intestine and suspends if from the abdominal wall is the ___? 2. The backbone encloses the ___? Name the tube-shaped structure located between the oropharynx and the esophagus. The notochor...