Polymers that are biocompatible are useful for various medical purposes such as tissue repair, reconstruction and wound healing. A method and composition for producing a biocompatible polymer formed from nucleic acids is disclosed. The nucleic acid polymer may be used to form a hybrid with an ...
Exploring base-pair-specific optical properties of the DNA stain thiazole orange Double-stranded DNA offers multiple binding sites to DNA stains. Measurements of noncovalently bound dyenucleic acid complexes are, necessarily, measuremen... DV Jarikote,N Krebs,S Tannert,... - Chemistry - A Europea...
When irreversibly attached, the motile cells continue to pour into the biofilm initiation, forming microcolonies. Subsequently, biofilms begin to express large amounts of extracellular polymers and exopolysaccharides, mainly represented by Pel, Psl and alginate, i.e., the central building blocks [51,...
Molecular recognition directed self‐assembly of supramolecular liquid crystalline polymers from complementary chiral components The self?assembly of intelligent supermolecular materials, for example, liquid crystalline polymers, is the subject of this communication. Employing units based on tartaric acid in the...
These inhibitors did not disintegrate the biofilm (Fig. 2g) or inhibit the metabolism of the Mtb residing in the biofilm (Fig. 2h). Biofilm formation requires nucleic acids and protein synthesis. Biofilm formation is an active process requiring metabolism by bacterial cells and depends on ...
Biofilm formation is a strategy of many bacterial species to adapt to a variety of stresses and has become a part of infections, contaminations, or beneficial interactions. In this study, we demonstrate that profound physiological changes permit Bacillus
nucleic acids, and some synthetic polymers, such as polyesters and polyamides, are produced by step-growth polymerization. On the other hand, chain-growth polymerization proceeds via successive intermolecular reactions between monomers and reactive sites on the polymer chain, with regeneration of the ...
The resulting synthetic polymers contain sequence‐defined regions of β‐sheet encoding amino acid sequences. Exploiting the pH responsiveness of the embedded sequences, protonation or deprotonation in water induces self‐assembly of the peptide strands at an intramacromolecular level, driving polymer ...
(νC–N) was found at ~ 1400–1410 cm − 1.34 In the cases of living cells and cells covered by collagen nanofibers, a band centered at 1236 cm − 1 originates from asymmetric phosphate stretching vibra- tions, which can be attributed to phosphodiester groups of nucleic acid in DNA....
The exopolysaccharide galactosaminogalactan (GAG) is an important virulence factor of the fungal pathogen Aspergillus fumigatus. Deletion of a gene encoding a putative deacetylase, Agd3, leads to defects in GAG deacetylation, biofilm formation, and virul