T cellsNUCLEOTIDE sequencingFollicular helper T-cell lymphomas (TFH lymphomas) were discussed in session V of the lymphoma workshop of the European Association for Haematopathology (EA4HP)/Society for Hematopathology (SH) 2022 meeting in Florence, Italy. The session focused on the morphologic ...
Follicular helper T cells (TFH) are able to closely interact with B cells to promote the formation of germinal centers (GCs). The stable cognate interaction between TFH and B cells in the GC is mutually beneficial to both cells for their development and function. Specifically, help B cells ...
T follicular helper (Tfh) cells are a subset of CD4 positive t helper cells that are critical for mounting immune responses against pathogens.
T follicular helper (Tfh) cells are a subset of CD4 positive t helper cells that are critical for mounting immune responses against pathogens.
CAR-T cell therapy targeting CD19 demonstrated strong activity against advanced B cell leukemia, however shows less efficacy against lymphoma with nodal dissemination. To target both B cell Non-Hodgkin’s lymphoma (B-NHLs) and follicular T helper (Tfh) cells in the tumor microenvironment (TME),...
Angioimmunoblastic T-cell lymphoma (AITL) is one of the most frequent entities of peripheral T-cell lymphoma. An AITL has two components: the AITL tumour cells, which have a T follicular helper (TFH) cell phenotype, and a surrounding and extensive tumour microenvironment that is populated with...
Under the control of specific cytokines and B-cell lymphoma 6 transcription factor (Bcl-6), the major transcription factor of TFH cells, TFH, can expand to the other distinct CD4 + T helper cells (TH1, TH2, and TH17) which exert a different role in the development of CRC. This ...
T follicular helper (Tfh) cells are a subset of CD4 positive t helper cells that are critical for mounting immune responses against pathogens.
IL-21 and T follicular helper cells Upon encounter with antigen, CD4(+) T cells differentiate into effector T(h) subsets with distinctive functions that are related to their unique cytokine p... WJ Leonard - 《International Immunology》 被引量: 262发表: 2010年 Follicular lymphoma tumor-infiltra...
Pathological diagnosis of T-follicular helper cell lymphoma 赵月 美国摘要: T 滤泡辅助细胞淋巴瘤 (T-FHCL) 是一种外周 T 细胞淋巴瘤,对它的认识几十年来一直在不断发展,世界卫生组织 2017 年分类将其分为三个亚类别。由于T-FHCL常有误导性的组织病理表现和未完全阐明的发病机制,其诊断具有挑战性,通常需要...