T-cell lymphomaCUTANEOUS T-cell lymphomaLYMPHOMAST cellsNUCLEOTIDE sequencingFollicular helper T-cell lymphomas (TFH lymphomas) were discussed in session V of the lymphoma workshop of the European Association for Haematopathology (EA4HP)/Society for Hematopathology (SH) 2022 meeting in Florence, Italy...
Follicular lymphoma cell niche: identification of a preeminent IL-4-dependent TFH–B cell axis C Pangault P Amé-Thomas T Fest Original Article14 Oct 2010 Leukemia The development and function of follicular helper T cells in immune responses Maogen Chen Zhiyong Guo Song Guo Zheng Review...
Follicular helperT cells(TFH) are essential B cell-help providers in the formation ofgerminal centers(GCs),affinity maturationofGCB cells, differentiation of high-affinity antibody-producing plasma cells, and production ofmemory B cells. The transcription factor (TF)B cell lymphoma6 (Bcl6) is at...
Angioimmunoblastic T cell lymphoma (AITL) is an aggressive tumor derived from malignant transformation of T follicular helper (Tfh) cells. AITL is characterized by loss-of-function mutations in Ten-Eleven Translocation 2 (TET2) epigenetic tumor suppressor and a highly recurrent mutation (p.Gly17...
Follicular helper T cells (TFH) are essential B cell-help providers in the formation of germinal centers (GCs), affinity maturation of GC B cells, differentiation of high-affinity antibody-producing plasma cells, and production of memory B cells. The transcription factor (TF) B cell lymphoma 6...
Abbreviations:CD, cluster of differentiation; BATF, basic leucine zipper transcriptional factor ATF-like; BCL, B cell lymphoma; ICOS, inducible t cell costimulatory; IL, interleukin; IRF, interferon regulatory factor; PD, programmed cell death protein; STAT,...
Abbreviations: CD, cluster of differentiation; BATF, basic leucine zipper transcriptional factor ATF-like; BCL, B cell lymphoma; ICOS, inducible t cell costimulatory; IL, interleukin; IRF, interferon regulatory factor; PD, programmed cell death protein; STAT...
Angioimmunoblastic T-cell lymphoma (AITL) is one of the most frequent entities of peripheral T-cell lymphoma. An AITL has two components: the AITL tumour cells, which have a T follicular helper (TFH) cell phenotype, and a surrounding and extensive tumour microenvironment that is populated with...
Follicular T-cell lymphoma is a recently described, rare neoplasm with the true incidence still unknown. It is a lymph node-based tumor in which the node shows a follicular pattern of growth. Immunohistochemistry confirms the cells of origin to be follicular helper T-cells and thus plays an im...
Abbreviations:CD, cluster of differentiation; BATF, basic leucine zipper transcriptional factor ATF-like; BCL, B cell lymphoma; ICOS, inducible t cell costimulatory; IL, interleukin; IRF, interferon regulatory factor; PD, programmed cell death protein; STAT, ...