[5] Makrides M, Gibson RA, McPhee AJ, et al. Neurodevelopmental outcomes of preterm infants fed high-dose docosahexaenoic acid: randomized controlled trial [J]. JAMA, 2009, 301(2): 175-182. [6] Lozoff B, Jimenez E, Smith JB. Double burden of iron deficiency in infancy and low socioec...
In recent years, more and more studies show that folic acid has an important role in the birth defects such as congenital disease and neural tube defects. It can effectively reduce the risk of having a baby with birth defects when the pregnant women have appropriate dose of folic acid. This...
It is now well established that folic acid deficiency (absolute or relative) is a predisposing factor to this type of malformation. Several randomized controlled trials showed that high-dose folic acid (4 mg) is an essential factor for prevention of neural tube defects recurrence and ...
although supplementation may be needed in low- birth-weight infants, in those who are breast-fed by mothers with folic acid deficiency (50 mcg daily), or in those with infections
For example, folinic acid has been used to correct the folate deficiency in cerebral folate deficiency disorder (a condition in which CSF folate level is abnormally lower than blood levels because of disturbed folate transfer across the blood-brain barrier), restoring CSF levels and improving ...
These conditions may be causing folate deficiency, require additional medications or a higher dose of folic acid, or further laboratory investigation. For example: Folic acid in dosages above 0.4mg daily may hide laboratory changes caused by pernicious anemia without halting the progression of neurolog...
Patients with folic acid deficiency should be encouraged to eat a diet rich in green leafy vegetables and fruits. Folic acid supplementation at a dose of 1mg daily is usually sufficient to prevent folic acid deficiency in certain high-risk patient populations (bariatric surgery, malnutrition, chronic...
It is often recommended that you take a B-complex supplement rather than individual B vitamins. Doing so can lead to imbalances and/or mask symptoms of deficiency. Folic acid supplements, for example, can sometimes mask a potentially dangerous B12 deficiency. ...
How does folic acid work? Folic acid is essential for making the DNA of cells. Thus, it is important for growth and development. It is also important for the formation of a healthy nervous system and the formation of red blood cells (RBCs). If there is a deficiency of folic acid, the...
for older adults to be aware of the relationship between folic acid and vitamin B12 because they are at greater risk of having a vitamin B12 deficiency. If you are 50 years of age or older, ask your physician to check your B12 status before you take a supplement that contains folic acid...