hippocampusfield CA1ultrastructurekainic acidstatus epilepticusThe ultrastructure of hippocampal field CA1 in rats was studied 14 days after status epilepticus induced by administration of kainic acid. Structural changes were seen in 40% of cells, predominantly interneurons, which showed both reversible ...
海马具有高度分化的片层结构,一方面,海马神经环路在片层中的分布有一定的空间规律,如锥体细胞胞体分布在锥体细胞层,而雪氏侧支突触分布于辐射层,且海马中存在一个三突触联系的回路,即穿通纤维-齿状回颗粒细胞层、苔状纤维-CA3区锥体细胞层、雪氏侧支-CA1区锥体细胞层等,因此,在海马中可以较准确地记录到特定神经...
The induction of long-term depression (LTD) was investigated in area CAI of hippocampal slices from adult rats. To produce LTD, prolonged low-frequency sti... Ursula,V.,Staubli,... - 《Brain Research》 被引量: 79发表: 1996年 Chemical LTD in the CA1 field of the hippocampus from young...
of rhythmic processes in the CA1 field of the hippocampus. Significance Statement The development of models describing a large complex of experimental data is an important aim of theoretical neuroscience. We propose an approach: models of separated aspects can be used as good initial conditions for...
1. Whole-cell patch-clamp recording has been used to study tetanus-induced synaptic potentiation of dual-component excitatory postsynaptic currents (EPSCs) in the CA1 region of rat hippocampal slices, following blockade of GABAA and GABAB receptor-mediated synaptic inhibition. 2. At a holding ...
2.3 Single-cell resolution, large-field-of-view 3P imaging in cortical L6 and deep imaging in CA1 through intact Cortex We performed 3P LFOV structural imaging of neurons in a cortical column and the stratum pyramidale (SP) layer of the CA1 region of the hippocampus in a transgenic mouse ...
the most conservative interpretation would be that some nonspecific aspect of emotionality or locomotion is affected, rather than a specific brain region. Interestingly, kindling, especially of the dorsalhippocampus, increases exploratory behavior (Hannesson et al., 2001). In thekainic acidepilepsy model...
Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade. We tested a theoretical prediction that patterns of excitatory input activity that consistently fail to activate target neurons sufficiently to induce syna... SM Dudek,MF Bear - 《Pr...
hippocampus place cells looming two-photon microscopy immersion Introduction The mechanical stability provided by mouse head fixation has facilitated the use of high-resolution functional microscopy,1,2,3,4 intracellular patch-clamp recording,5,6,7,8 and large-scale single-unit recording in behaving mi...
(A) Mice were chronically implanted with single recording electrodes at medial prefrontal cortex (mPFC), medial septum (MS), mediodorsal thalamic nucleus (MD), nucleus accumbens (NAc), and the CA1 area of the dorsal hippocampus (CA1). (B) Representative photomicrographs of electrodes implanted...