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Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones Cell, 186 (2023), pp. 2748-2764.e22, 10.1016/j.cell.2023.05.003 View PDFView articleView in ScopusGoogle Scholar 32 W.H. Habig, M.J. Pabst, W.B. Jakoby Glutathione S-transferases. The first enzymatic...
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Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones. Cell 186, 2748–2764 (2023). Jiang, X., Stockwell, B. R. & Conrad, M. Ferroptosis: mechanisms, biology and role in disease. Nat. Rev. Mol. Cell Biol. 22, 266–282 (2021). Article PubMed PubMed...
However, depleting Alox15 failed to rescue acute renal failure induced by Gpx4 depletion [45]. ALOX12 is essential for TP53-mediated tumor suppression in various cancer cell lines (e.g., U2OS, H1299, and A549 cells) as well as in murine models [46]. This effect is independent of ACSL4...
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