The ability to predict local structural features of a protein from the primary sequence is of paramount importance for unravelling its function in absence of experimental structural information. Two main factors affect the utility of potential prediction tools: their accuracy must enable extraction of re...
The invention relates to a method and device for changing the functional features, with no alteration thereof, of a protein preparation, preferably isolates or concentrates from plant seed-based proteins. The inventive method consists in heating a proteinic preparation for producing perishable or dry ...
Intramembrane proteases regulate diverse processes by cleaving substrates within a transmembrane segment or near the membrane surface. Bacillus subtilis SpoIVFB is an intramembrane metalloprotease that cleaves Pro-sigma(K) during sporulation. To elucidate features of Pro-sigma(K) important for cleavage by...
Each type of protein has a particular three-dimensional structure, which is determined by the order of the amino acids in its polypeptide chain. A protein’ s structure begins with its amino acid sequence, which is thus considered its primary structure. The next level of the organization include...
None of the cases demonstrated significant nuclear atypia, mitotic activity or necrosis. Tumors appeared circumscribed in all cases. Microcalcification was seen in three cases (21.4%). Glial fibrillary acidic protein (GFAP) was negative in the oligodendrocyte-like cells in all cases but was positive...
P. et al. CpG islands influence chromatin structure via the CpG-binding protein Cfp1. Nature 464, 1082–1086 (2010) Article ADS CAS PubMed PubMed Central Google Scholar Mikkelsen, T. S. et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448, ...
Conclusions Our findings demonstrate the potential of a graph genome approach to reveal important functional features of NRSs in pig populations.Background Pigs (Sus scrofa) are crucial to human society, serving as a valuable source of animal protein and holding immeasurable medical potential due to ...
The frequency fof a referen... K Uchiyama,S Kato - US 被引量: 41发表: 2004年 Different Effects of Guanine Nucleotides (GDP and GTP) on Protein-Mediated Mitochondrial Proton Leak In this study, we compared the influence of GDP and GTP on isolated mitochondria respiring under conditions ...
In addition, a special emphasis is devoted to the recent structural and functional discoveries in the field of polyomavirus agnoprotein which is expressed only by JCV, BKV, and simian virus 40 genomes.doi:10.1002/jcp.27715A. Sami Saribas
The ectopic expression of a defined set of transcription factors can experimentally reprogramme somatic cells into other cell types, including pluripotent cells. This method enables exploration of the molecular characteristics of pluripotency, cell speci