KUMAR A,MOHANTY N N,CHACKO N,et al.Structural features of a highly conserved omp16 protein of pasteurella multocida strains and comparison with related peptidoglycan-associated lipoproteins(PAL)[J].Indian J Microbiol,2015,55(1):50-56.Kumar A, Mohanty N N, Yogisharadhya R, Chacko N and ...
The ability to predict local structural features of a protein from the primary sequence is of paramount importance for unravelling its function in absence of experimental structural information. Two main factors affect the utility of potential prediction tools: their accuracy must enable extraction of re...
Explaining the diversity and complexity of protein localization is essential to fully understand cellular architecture. Here we present cytoself, a deep-learning approach for fully self-supervised protein localization profiling and clustering. Cytoself leverages a self-supervised training scheme that does ...
The rapid advances in proteomic analyses coupled with the completion of multiple genomes have led to an increased demand for determining protein functions. The first step is classification or prediction into families. A method was developed for the prediction of protein family based only on protein ...
A fairly close match could be found for only a small number of non-globins, nearly all of which are very long and most of which are polyproteins. Thus, the features of the globin sequences that are conserved and define its fold and function are essentially unique to that family....
P. et al. CpG islands influence chromatin structure via the CpG-binding protein Cfp1. Nature 464, 1082–1086 (2010) Article ADS CAS PubMed PubMed Central Google Scholar Mikkelsen, T. S. et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448, ...
BofA protein inhibits intramembrane proteolysis of pro-σK in an intercompartmental signaling pathway during Bacillus subtilis sporulation Bacillus subtilis is a bacterium that undergoes a developmental program of sporulation in response to starvation. At the core of the program are σ factors... Zhou ...
MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) are protein- serine/threonine kinases that are activated by ERK or p38 and phosphorylate eIF4E, which... Uedaa,Takeshi,Sasakia,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 211发表...
et al. UV irradiation induces a non-coding RNA that functionally opposes the protein encoded by the same gene. Cell 168, 843–855.e13 (2017). This paper describes dual coding and non-coding functions of the ASCC3 locus, with a switch from long, coding transcript production induced by ...
Each type of protein has a particular three-dimensional structure, which is determined by the order of the amino acids in its polypeptide chain. A protein’ s structure begins with its amino acid sequence, which is thus considered its primary structure. The next level of the organization include...