gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been ...
25、fcgr3a 26、在人的基因组中,fcgr3a基因(ncbi gene id:2214)包含6个外显子,即外显子1、外显子2、外显子3、外显子4、外显子5和外显子6(图1)。人fcgr3a mrna的核苷酸序列为nm_001127595.2,人fcgr3a的氨基酸序列为np_001121067.1(seq id no:2)。基于转录本nm_001127595.2及其编码蛋白np_001121067.1的核...
这个基因是一个假定的癌基因,编码一个属于丝氨酸/苏氨酸激酶亚家族的蛋白质,包含sh2样(SRC同源2样)结构域。该基因在8个卵巢癌细胞系中的2个和15个原发性卵巢肿瘤中的2个被扩增和过度表达。过度表达导致人导管胰腺癌亚群的恶性表型。编码蛋白是一种普通的蛋白激酶,能够对几种已知的蛋白进行磷酸化。 This gene i...
gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been ...
This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear...
FCGR3A抗体;FCGR3A多克隆抗体 Description This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as w
The impact of the FCGR3A gene polymorphism on response rate was not noted in the CHOP group. In terms of overall or event-free survival, no difference was found according to FCGR3A or FCGR2A alleles. The FCGR3A single nucleotide polymorphism (SNP) is predictive of response to R-...
Gene ID: 2214 种属: Homo sapiens 基因序列编号: NM_000569 基因描述: Homo sapiens Fc gamma receptor IIIa (FCGR3A), transcript variant 1, mRNA 基因编码区: atgggtggaggggctggggaaaggctgtttacttcctcctgtctagtcggtttggtccct ttagggctccggatatctttggtgacttgtcctctccagtgtggcatcatgtggcagctg ctcctcccaactgc...
To provide an overview ofpolymorphisms, we analysed the 1000 Genomes project database and found a total of 234 polymorphisms within thegene, of which 69%, 16%, and 15% occur in the intron, UTR, and exon regions respectively. Additionally, only 16% of all polymorphisms had a minor allele ...
(CD16a) CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA P08637 BC033678 >85%, as determined by Coomassie blue stained SDS-PAGE Escherichia coli His tag C-Terminus, GST tag N-Terminus This gene encodes a receptor for the Fc portion of immunoglobuli n ...