J. (1995). Fatty acid beta-oxidation in peroxisomes and mitochondria: the first, unequivocal evidence for the involvement of carnitine in shuttling propionyl-CoA from peroxisomes to mitochondria. Biochemical and Biophysical Research Communica- tions, 213(3), 1035-1041....
Background/Aims: Abnormal fatty acid β oxidation has been associated with obesity and type 2 diabetes. Resistin is an adipokine that has been considered as a potential factor in obesity-mediated insulin resistance and type 2 diabetes. However, the effect of resistin on fatty acid β oxidation ...
Expression of enzymes involved in fatty acid oxidation becomes upregulated through fatty acids behaving as ligands that bind to peroxisome proliferator-activated receptors; these transcription factors form homo-/heterodimers and translocate to the nucleus, where they alter gene expression involved in the p...
acid oxidation rates, and disruption of fatty-acid oxidation leads to stem cell differentiation through a mechanism mediated by peroxisome proliferator-activated receptor δ11. Our study finds that during infection HSCs take up FFA as a result of upregulation of the fatty-acid translocase CD36 on ...
fatty acid metabolism. Peroxisome proliferator-activated receptors (PPARs), for example, are ligand-activated transcription factors that regulate the expression of fatty acid oxidation genes. Sterol regulatory element-binding proteins (SREBPs) regulate gene expression in fatty acid production and absorption...
Peroxisomes are cellular organelles that play an important role in beta-oxidation of very-long-chain fatty acids, degradation of phytanic acid by alpha-oxidation, degradation of hydrogen peroxide, as well as synthesis of bile acids and plasmalogen (an important component of cell membranes and myelin...
Peroxisome proliferator-activated receptor-alpha accelerates alpha-chlorofatty acid catabolismmyeloperoxidaselipid biochemistryfatty acidfatty acid... Palladino, Elisa N. D.Wang, Wen-yiAlbert, Carolyn J.Langhi, CedricBaldan, AngelFord, David A. - 《Journal of Lipid Research》 被引量: 0发表: 2017年...
27 August 2015 FABP4 reversed the regulation of leptin on mitochondrial fatty acid oxidation in mice adipocytes Lu Gan*, Zhenjiang Liu*, Weina Cao, Zhenzhen Zhang & Chao Sun Fatty acid binding protein 4 (FABP4), plays key role in fatty acid transportation and oxidation, and incre...
green tea epigallocatechin gallate, resveratrol, capsaicin and curcumin, have been reported to increase lipolysis and induce fatty acid β-oxidation through modulation of hormone sensitive lipase, acetyl-coA carboxylase, carnitine acyl transferase and peroxisome proliferator-activated receptor gamma coactivator...
(Bandyopadhyay et al., 2006). In addition, insulin is known to inhibit the expression of beta-oxidation enzymes in the hepatocyte. Accumulation of fat in the liver results in not only liver steatosis, but also in imbalance in free fatty acid availability, and impairment in the oxidative ...