Protocol. Experimental protocol for the four experimental groups (Torpor, Cold exposure, Fasting, and Control). Full size image After confirming the presence of torpor (usually around 10.30–11.00 am) in the Torpor group, by visually observing the infrared images of the mouse recorded by an infra...
Fasting is known to influence learning and memory in mice and alter the neural networks that subserve these cognitive functions. We used high-resolution functional MRI to study the impact of fasting on resting-state functional connectivity in mice follow
The cut-off value of fasting glucose levels for significant association with degenerative RCT was found to be 90.5 mg/dL. Fasting glucose level ≥ 90.5 mg/dL had a “poor” performance rating for predicting degenerative RCT, with an AUC of 0.68 (95% CI [0.62–0.75];P < .001) ...
Feasibility of Ramadan fasting in adults with type 1 diabetes: an observational studydoi:10.1007/s13410-017-0575-0Abdulwahab ElbarshaRafik ElmehdawiImhemed EljazwiNajat BuzaidNezar MahgobMaisoon ElhemriSpringer India
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Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/functi... The glycolytic enzyme glucokinase plays an important role in the regulation of insulin secretion and recent studies have shown that mutations in the...
Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial. Nature Communications. doi: 10.1038/s41467-020-16138-3. 2. New Peer-Reviewed Research Shows Fasting Mimicking Diets May Enhance Effectiveness of Chemothe...
Male Wistar rats were subjected to 48 days of IF (eight repeated cycles of three days of fasting and three days refeeding) or an isoenergetic 20% CER. The IF mice showed up regulation of genes for both lipid storage (PPARγ 2 and Fsp27) and fat oxidation (MCPT1) ref...
Thereafter, cells were cultured in regular medium for an additional 14 d. Finally, cells were fixed and stained with sulforhodamine B and cell colonies were counted. d, T47D and ZR-75-1 cells were plated in 96-well plates and exposed to STS, TMX at the indicated concentrations or their ...
Patients using the FMD as an adjunct to chemotherapy did not experience more grade III/IV adverse events than patients who did not follow a diet, despite the fact that they were not prescribed dexamethasone in concert with FEC/AC. This suggests that the FMD may obviate the need for dexamethas...