We expect that an altered tongue microenvironment will result in a change of taste sensitivity as detected by chemical gustometry along with a changed neural response to visual food cues in reward processing regions as assessed by functional MRI. The main limitation of this study is that the ...
www.nature.com/scientificreports OPEN FGF21 does not require interscapular brown adipose tissue and improves liver metabolic received: 09 March 2015 profile in animal models of obesityaccepted: 22April 2015 and insulin-resistancePublished: 08 July 2015 Barbara Bernardo1, Min Lu2,3, Gautam ...
The improvement at the whole body level was reflected by increased muscle mitochondrial capacity for palmate oxidation, but these changes were not due to an increase in β-HAD, and based on the CoA to carnitine ratio, were not likely due to change in fatty acid entry into the mitochondria. ...
The accumulation of tissue TAG may not only be due to a decrease in the oxidation rate of fatty acids, but also to an increase in fatty acid delivery via plasma TAG and FFA. It is further proposed that intra-cel- lular TAG per se may not cause insulin resistance, but instead may be ...
Indeed, a recent meta-analysis found that pre-, pro- and symbiotic-supplementation reduces fasting insulin levels, hy- perinsulinaemia and circulating AGEs in individuals with diabetes [184], suggesting the link between the microbiome, glucose homeostasis and AGE burden is an important one. However...
Although few studies have directly elucidated the effects of high-temperature stress on mitochondrial genome expression levels, as an essential component of cellular metabolism, mitochondria should play a crucial role in this process. Indeed, the heart of rainbow trout (Oncorhynchus mykiss) held at ...