The catalytic activity, the ability to form dimers, and the binding of FAD are associated with the carboxyl-terminal domain of the protein. Our findings identify Erv2p as the first microsomal member of the Erv1p/Alrp protein family of FAD-linked sulfhydryl oxidases. We propose that Erv2p ...
LSD1 is a unique demethylase that does not contain the jumonji domain but as a flavoenzyme does have the FAD-dependent amine oxidase domain1. Our present study clearly indicates that LSD1 negatively regulates energy expenditure that can be reversed by inhibiting LSD1 function and FAD biosynthesis...
Erv2p is an FAD-dependent sulfhydryl oxidase that can promote disulfide bond formation during protein biosynthesis in the yeast endoplasmic reticulum. The structure of Erv2p, determined by X-ray crystallography to 1.5 Å resolution, reveals a helix-ric
Thus, collectively, the transmembrane domains of the Steap, ferric reductase, and NADPH oxidase protein families place each of these within the greater “ferric reductase domain” (FRD) superfamily (9). In this light, members of the ferric reductase and NADPH oxidase families utilize cytosolic ...
FAD is a key coenzyme that are required for catalytic activity of several enzymes including Interleukin 4 Induced 1 (IL-4I1), a glycosylated protein that is secreted from myeloid cells as well as B and T cells [9,10]. IL-4I1 belongs to the L-amino-acid oxidase (LAAO) family of fl...
FAD is a key coenzyme that are required for cata- lytic activity of several enzymes including Interleukin 4 Induced 1 (IL-4I1), a glycosylated protein that is secreted from myeloid cells as well as B and T cells [9, 10]. IL-4I1 belongs to the L-amino-acid oxidase (LAAO) family ...
glycogen糖原cellulose纤维素cellulase纤维素酶selectivity选择性substrate底物holoenzyme全酶cofactor辅因子coenzyme辅酶oxidase氧化酶metabolism新陈代谢assimilation同化作用catabolism异化作用 metabolite代谢产物biological oxidation 生物氧化cytochrome细胞色素rotenone鱼藤酮amytal阿密妥antimycinA抗霉素A cyanide氰化物glycolysis糖酵解ethano...
Some specific constructs that are described employ the following protein coding sequences: the APP770 cDNA; the APP770 cDNA bearing a mutation at amino acid 669, 670, 671, 690, 692, 717, or a combination of these mutations; the APP751 cDNA containing the KPI protease inhibitor domain ...
Measurement of blood glucose concentration is essential for diabetic patients to suitably control their blood sugar levels. For daily checking of blood sugar levels, for example, glucose sensors and simple blood glucose self-monitoring kits using glucose oxidase (also referred to as “GOD” in the ...
(2000) Aryl-alcohol oxidase protein sequence: a comparison with glucose oxidase and other FAD oxidoreductases. Biochim. Biophys. Acta 1481, 202- 208.Aryl-alcohol oxidase protein sequence: a comparison with glucoseoxidase and other FAD oxidoreductases. Varela E,Jesus Martinez M,Martinez A. T. ...