Human choroideremia protein contains a FAD-binding domain - Koonin - 1996 () Citation Context ...d’ alignments provide this view (Figure 4). A dinucleotide-binding motif positioned at bases 11–21 of Rab Escort Protein is characterized by bulky hydrophobic residues followed by a glycine-rich ...
Interestingly, the mutant generated by changing the first glycine of the proposed FAD-binding domain (GxGxxG) to alanine revealed catalytic activities, but was lower than those seen with the unmodified form. The conversion of the first glycine to alanine markedly increased and decreased the K m ...
We report the crystal structure of the FAD/NADPH‐binding domain (FAD domain) of the biotechnologically important Bacillusmegaterium flavocytochrome P450BM3, the last domain of the enzyme to be structurally resolved. The structure was solved in both the absence and presence of the ligand NADP+, ...
According to the predicted 3D structure of ETF:QO, the two mutations are located within the flavin adenine dinucleotide (FAD) binding domain; however, the two residues do not have direct interactions with the FAD ligand. Using molecular dynamics (MD) simulations and normal mode analysis (NMA),...
例句 释义: 全部 更多例句筛选 1. Cloning and Expression of Inducible Nitric Oxide Synthase FAD-Binding Domain and Its Binding Activity to FAD 诱生型一氧化氮合酶FAD结合区的克隆、表达和活性鉴定 www.ilib.cn隐私声明 法律声明 广告 反馈 © 2025 Microsoft...
N-Terminus determination: FAD and NADP binding domain mapping of hog liver flavin-containing monooxygenase by tandem mass spectrometry Author links open overlay panelShenheng Guan a b, Arnold M. Falick a b, John R. Cashman a bShow more
Structure determination of the N-terminal thioredoxin-like domain of protein disulfide isomerase using multidimensional heteronuclear 13C/15N NMR spectroscopy. Biochemistry 35, 7684–7691 (1996). Article CAS Google Scholar Kemmink, J. et al. The structure in solution of the b domain of protein ...
). The N-terminal domain of sarco- sine oxidase adopts the Rossmann fold and binds FAD. The first a-helix (a-helix 1) contains a GXXXG motif that stabilizes an interaction between the a-helix and the first b-strand (b-strand ...
Here we identify high affinity FAD and iron biding sites and characterize a single b-type heme binding site in the Steap3 transmembrane domain. Furthermore, we show that Steap3 is functional as a homodimer and that it utilizes an intrasubunit electron transfer pathway through the single heme ...
Our previous work has demonstrated that the native human PDGF-BB was added a collagen-binding domain (CBD), TKKTLRT, to develop a collagen-based PDGF targeting delivery system. Here, we showed that this CBD-fused PDGF-BB (CBD-PDGF) could bind to collagen membrane efficiently. We used the...