The molecular basis is a single G to A mutation in position 1691 (the factor V Leiden [FVL] mutation). The prevalence of the FVL mutation in white populations has been reported to be 2% to 15%. The relationship between the FVL mutation and increased risk of adverse obstetric outcomes is...
P45 Factor V Leiden mutation and pregnancy complications The objective of the study was to determine the prevalence of the factor V Leiden (FVL) mutation and its association with obstetric complications, blood lo... UKVRB Hellgren - 《Thrombosis Research》 被引量: 0发表: 2009年 Factor V Leiden...
The meaning of FACTOR V LEIDEN is a point mutation producing an abnormal version of factor V that is resistant to inactivation and causes prolonged clotting of blood.
OBJECTIVE: We sought to estimate the frequency of pregnancy-related thromboembolic events among carriers of the factor V Leiden (FVL) mutation without a personal history of thromboembolism, and to evaluate the impact of maternal and fetal FVL mutation carriage or other thrombophilias on the risk of...
The aim of the study was to determine if carriership of the factor V (FV) Leiden mutation (activated protein C [APC] resistance) is higher in women who have had of placental abruption during pregnancy.doi:10.1046/j.1471-0528.2003.02369.xMartin...
Factor V Leiden, pregnancy complications and adverse outcomes: the Hordaland Homocysteine StudyDiscussion: FVL mutation is a significant risk factor for pregnancy complications and adverse outcomes, and MTHFR 677CT/TT genotype can further enhance the risk of stillbirth.E. Nurk...
Presents a study which was conducted to determine whether women with factor V Leiden mutation are at an increased risk for recurrent pregnancy loss. Number of patients referred for evaluation of recurrent spontaneous abortion; How the prevalence of factor V Leiden mutation was determined; Cause of ...
I am about 7 weeks pregnant now. My mom was diagnosed with Factor V Leiden 2 months ago and i had to get tested for it since its genetic.
作者: Peter Clark and Sara Twaddle and Isobel D Walker and Linda Scott and Ian A Greer 摘要: Summary The factor V Leiden (FVL) mutation is associated with vascular complications in pregnancy, and routine screening of all pregnant women has been suggested. We did a prospective, unselected ...
(redirected fromFactor V Leiden mutation) Thesaurus Medical Legal Acronyms Encyclopedia mu·ta·tion (myo͞o-tā′shən) n. 1.The act or process of being altered or changed. 2.An alteration or change, as in nature, form, or quality. ...