A change in the genes or chromosomes of an organism. Mutations occurring in the reproductive cells, such as an egg or sperm, can be passed from one generation to the next. Most mutations have harmful effects, but some can increase an organism's ability to survive. A mutation that benefits...
Our study confirms that women heterozygous for factor V Leiden have an increased risk of developing HELLP syndrome, while the most frequent mutations of the prothrombin and MTHFR gene do not play a major role in the pathogenesis of HELLP syndrome....
Evaluation of Factor V Leiden, Prothrombin and Methylenetetrahydrofolate Reductase Gene Mutations in Patients with Severe Pregnancy Complications in Northe... Background: Thrombosis in placenta may lead to severe pregnancy complications. Most important inherited thrombophilias are factor V Leiden mutation,...
2021 Among the 20 or so known genetic risk factors, the most common include the factor V Leiden mutation, prothrombin gene mutations and deficiencies in protein C, protein S and antithrombin. Dr. Keith Roach, oregonlive, 1 Nov. 2021 These examples are programmatically compiled from various ...
Factor V Leiden and Prothrombin Gene 20210A Variant in Neonatal Thromboembolism and in Healthy Neonates and Adults: A Study in a Single Center. This study was conducted to identify the prevalence of FV1691A and PT20210A mutations in neonates with symptomatic thromboembolism and in healthy neonates...
He was diagnosed as heterozygous for the FVL mutation and with stroke due to arterial thrombus in the left middle cerebral arterial territory. We suggest that thrombophilic mutations should be considered in the etiology of acute stroke in pediatric patients.F. AtaF. AlehanH. Verdi...
However, testing for FVL mutations, which was not routinely available in our hospital, was not performed in our patient at initial presentation. The patient was treated with acetylsalicylic acid. Nine months later, she presented with mild blurry vision in the LE. Visual acuity was 20/400 in ...
RESULTS: APCR and factor V Leiden mutations were significantly more prevalent in all recurrent pregnancy loss patients in this study as compared to controls, 38% (30/78) and 19% (15/78) in contrast to 8% (11/139) and 6% (8/139), respectively. All three groups in the study were ...
因子V 1. A study on the correlations between pathogenesis of Budd-Chiari syndrome andFactor VLeiden and Factor Ⅱ G20210A mutations; 布加综合征与凝血因子V Leiden及凝血酶原基因G20210A突变的关系研究 2. Western blot of human plasma factor V and its clinical application; ...
Low level of HIV-1C integrase strand transfer inhibitor resistance mutations among recently diagnosed ART-naive Ethiopians With the widespread use of Integrase strand transfer inhibitors (INSTIs), surveillance of HIV-1 pretreatment drug resistance is critical in optimizing anti... M Kiros,DA Tefera,...