Note: Factor V Leiden is inherited as an autosomal dominant trait requiring that only one parent pass on a copy of the defective gene on a chromosome other than a sex chromosome. When both parents carry the defective gene, factor V Leiden is inherited as a recessive, more serious condition....
Factor V Leiden is the most common inherited risk factor for the development of thrombosis. The factor V Leiden mutation is a single point mutation in the gene coding for factor V, a substitution of adenine for guanine at the nucleotide position 1691, which results in the replacement of the ...
We investigated the presence of the gene mutation of factor V, FV ^l)6Q or factor V Leiden, responsible for activated protein C resis- nce, in DNA samples of 127 probands and 188 relatives from 128 jinhes with antithrombin deficiency.The factor V mutationwas iden- ned in 18 families. Ni...
Molecular Testing for Factor V Leiden and Prothrombin Gene Mutations in Inherited ThrombophiliaFactor IIFactor V LeidenFVLProthrombinThrombophiliaWe report an 81-year-old female with a heterozygous factor V Leiden mutation who developed purpura fulminans. Digital necrosis, a characteristic clinical feature ...
FACTOR-V LEIDEN: A RISK FACTOR FOR CEREBRAL PALSY 来自 Semantic Scholar 喜欢 0 阅读量: 11 作者:K Harum,A Hoon,J Casella 摘要: Inherited and acquired thrombophilic disorders have recently been associated with cerebral palsy (CP) and complications in pregnancy. Thrombophilic disorders are not ...
Background: Factor V Leiden (FVL) and prothrombin gene mutation (PGM) are common inherited thrombophilias. Retrospective studies variably suggest a link be... Rodger,A Marc - 《Plos Medicine》 被引量: 244发表: 2010年 Effect of second and third generation oral contraceptives on lipid metabolism...
Factor V Leiden mutation is a common genetic risk factor for venous thrombosis. It has been documented in up to 65% of patients with unexplained venous thromboembolism. This genetic mutation is now known to be the most common inherited cause of activated protein C (APC) resistance. Recently, ...
Inherited resistance to activated protein C (APC) has been recently recognized as a novel cause underlying venous thrombophilia. In most cases APC resistance is due to a single point mutation in the factor V gene leading to a replacement of Arg506 with Gln (factor V Leiden). Factor V Leiden...
Factor V LeidenthrombosismutationprothrombinNormal hemostasis requires balanced regulation of prothrombotic and antithrombotic factors. Inherited alteration of factor V and prothrombin gene, the G20210A mutation, increases the resistance of factor V to degradation and booster production of prothrombin ...
Ischemic strokes are one of the leading causes of death worldwide. The aim of this meta-analysis is to elaborate on the role of inherited predisposition to thrombophilia in the etiology of ischemic strokes in young adults. The keywords factor V Leiden (F