factor V Lei·den -ˈlī-dᵊn 1 : a point mutation producing an abnormal version of factor V that is resistant to inactivation and causes prolonged clotting of blood 2 also factor V Leiden thrombophilia : a genetic disorder caused by factor V Leiden that is marked by an ...
This article will review the factor V Leiden mutation, its association with VTE, and the genetic inheritance pattern and ethnic distribution. Oral contraceptive use, pregnancy, and hormone replacement therapy in women with the Leiden mutation will be discussed. Screening issues and management for all...
factor-V Leiden A common mutation of coagulation factor-V gene, which is found in 3 to 8% of Caucasians, and results in resistance to activated C protein and an increased risk in deep-vein and other thromboses. Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved....
Synonyms for Factor V Leiden mutation in Free Thesaurus. Antonyms for Factor V Leiden mutation. 34 synonyms for mutation: anomaly, variation, deviant, freak of nature, change, variation, evolution, transformation, modification, alteration, deviation...
V Leiden 第五凝血因子；莱登第五因子 第五凝血因子 检验第五凝血因子(Factor V leiden)上的G1691A突变：造成容易产生血栓的体质(血栓病, thrombophilia)。北美洲有 5% 的人遗传有莱登第五因子 ( Factor V Leiden )﹐影响凝血功能。 年长﹑肥胖﹑抽烟﹐与及曾经出现过静脉栓塞症状的人士﹐再次...
Twitter Google Share on Facebook (redirected fromFactor V Leiden mutation) Thesaurus Medical Legal Acronyms Encyclopedia mu·ta·tion (myo͞o-tā′shən) n. 1.The act or process of being altered or changed. 2.An alteration or change, as in nature, form, or quality. ...
and Caribbean StudiesinLeiden. wdl.org wdl.org 这本pustaha 书叙述的是对抗邪恶的保护方式,出自位于莱顿的KITLV/荷兰皇家东南亚和加勒比研究所的藏品。 wdl.org wdl.org Similar to material intensity the energy intensity cannot be used to quantify specific environmental pressures (e.g. ozone depletion) ra...
another a crossing-over event were ,*most likely explanations for the observed inheritance patterns.In six families with type I or II antithrombin deficiency (reactive sitepleiotropic effect), 11 of the 12 individuals with both antithrombin ..iiciency and the factor V mutation developed thrombosis....
Factor V Leiden (FVL) is the most common monogenic disorder that causes activated protein C (APC) resistance, creating hyper-coagulation. The mutation shows an uneven geographic distribution, significantly high in European populations. The mutation is believed to have originated approximately 20 000 ye...
Resistance to activated protein C, caused by a mutation in the Factor V gene, has been shown to be associated with thrombotic disease. We investigated the role of the Factor V Leiden mutation in patients with aPL. We studied 99 patients with high-titer aPL by amplification of genomic DNA ...