Rifampicin, one of the important anti-TB drugs, was reported to exhibit variable bioavailability and is classified as a class II drug in the Biopharmaceutic Classification System, (less soluble and highly permeable), thus, factors affecting rate and extent of dissolution would determine its ...
Biological factors affecting the radioprotective efficiency of s-2[3-aminopropylamino]ethyl phosphorothioic acid (WR-2721): LD5030 doses Radiat. Res., 44 (1970), pp. 621-628 CrossrefView in ScopusGoogle Scholar 46. J.M. Yuhas Active versus passive absorption kinetics as the basis for sele...
In vitro and in vivo experiments have documented that ingested nucleotides increased iron absorption, perhaps affectingxanthine oxidase.224Although in vitro studies showed that added nucleotides enhanced the growth ofbifidobacteria, conflicting results have been obtained on the influence of dietary nucleotides...
In the NDD-CKD population, the non-inferiority of vadadustat compared with darbepoetin alfa for MACE was not demonstrated. Vadadustat has been rejected by the FDA on safety concerns regarding thromboembolic events and a case of severe drug-induced liver injury reported in phase 2 trial data....
Development of inhibitors is a serious matter affecting 1.5–3% of patients with hemophilia B. Thus, successful eradication of inhibitor may be challenging and require rituximab, with or without desensitization therapy.[20] Inhibitors in hemophilia B patients have been associated with the development of...
More in particular, this invention relates to human monoclonal antibodies or fragments thereof modified in different ways affecting the size of the antibody and not the affinity thereof so to partially inhibit in a variable maximal manner a coagulation factor. These may be used as antithrombotic ...
Fig. 6: The FDA-approved drug Osimertinib binds with Mtb EF-Tu and inhibitsMycobacteriumgrowth. a,bThermal unfolding curves and unfolding transition midpoints of EF-Tu and EF-Tu/Osimertinib were detected by the Nano-DSF method.c–fOsimertinib did not affectE. coligrowth, but significantly inhi...
Objectives This study sought to determine whether known genetic, drug, dietary, compliance, and lifestyle factors affecting clopidogrel absorption and meta... AL Frelinger,DL Bhatt,RD Lee,... - 《Journal of the American College of Cardiology》 被引量: 191发表: 2013年 Gender norms and economic...
DrugCharacteristics Drugs used in iron-deficiency anaemia Iron Oral formulations Ferrous sulphateFerrous fumarateFerrous gluconatePolysaccharide–iron complexSodium feredetate These oral formulations have only marginal differences in the efficiency of iron absorption. Dosage is adjusted to provide similar content...
Factors affecting plasmid production in Escherichia coli from a resource allocation standpoint. Microb. Cell Fact. 2009, 8, 27. [Google Scholar] [CrossRef] [PubMed] [Green Version] Panayotatos, N. Recombinant protein production with minimal-antibiotic-resistance vectors. Gene 1988, 74, 357–363...