近日,华中科技大学李志明等研究人员在Cell Regeneration上发表了题为“The emerging and diverse roles of F-box proteins in spermatogenesis and male infertility”的综述文章,系统性地总结了F-box蛋白家族在男性生殖和精子发生领域的相关研究成果,并对该...
Among the several different E3 enzyme families, the SCF (Skp1-Cullin-F box protein) is one of the largest and best characterized. F-box proteins, in addition to the loosely conserved F-box motif that binds Skp1, often carry typical protein interaction domains and are proposed to recruit ...
2007 . F-box proteins that contain sugar-binding domains . Bioscience, Biotechnology, and Biochemistry 71 , 2623 – 2631 .Yoshida Y (2007) F-box proteins that contain sugar-binding domains. Biosci Biotechnol Biochem 71:2623–2631Yoshida Y (2007) - F-box proteins that contain sugar-binding ...
植物发育中F-box蛋白的功能研究进展 ABVANCES IN FUNCTIONAL STUDIES OF F-BOX PROTEINS IN PLANT DEVELOPMENT 目 录 TOC \o 1-3 \h \z \u 摘要 4 Abstract 4 前言 5 F-box蛋白的发现 6 F-box蛋白的结构 6 植物 F-box蛋白的功能 8 F-box蛋白与植物生长发育 8 4.1.1 花器官发育 8 4.1.2自交不...
structure and function of F-box proteins and reveal that this protein family has an important role in life. Furthermore, we indicate that F-box proteins are attractive candi- dates in the disease therapy and drug interaction. Key words: F-box protein; function; ubiquitin proteasome pathway; ...
生命活动中具有广泛而重要的作用,并指出了F-box蛋白将为阐明疾病发生机制提供新的线索,可望成 为疾病治疗中药物作用的靶向位点。 关键词:F-box蛋白;泛素-蛋白酶体途径;SCF复合体 中图分类号:Q51 文献标识码:A F-boxproteinsandtheirfunctions WANGXiu-yan ...
摘要:泛素连接酶作为一种翻译后效应器,对细胞生命活动的正常运行至关重要。而泛素连接酶SCF(Skp1-Cullin-F-boxprotein) 复合体重要组件—F-box蛋白的主要作用是对靶蛋白的特异性识别。作为许多生理病理过程的效应分子,它广泛存在于真核生物,参与了众多的细胞机制,其对底物的特异性识别是蛋白元件在特定时空功能终止的...
图1 F-Box蛋白家族在病毒-宿主相互作用中发挥的功能 Figure 1 Functions of FBPs in virus-host interactions The FBPs exhibit diverse functional roles in virus-host interactions based on their specific targets. FBPs can exert antiviral effects by degrading viral proteins and activating interferon signalin...
F-box proteins are attractive candi-dates in the disease therapy and drug interaction.Key words: F-box protein; function; ubiquitin proteasome pathway; SCF complex文章编号 : 1004-0374(2008)05-0807-05在真核生物中广泛存在着一类被称为 F-box 的蛋白家族,该蛋白家族的共同特征是含有 F-box 结构域...
boxproteincharacterizedbyanF-boxmotifisasubunitofSCFcomplex,whichworksasdeterminantinsubstraterecognitionCurrently,manyF-boxproteinshavebeenidentifiedinplantswhichareinvolvinginhormone(eg,ethylene(auxin)gibberellinandjasmonate)signaltransductionandbiologicalprocesses,suchasself-incompatibilityandfloraldevelopmentF-boxproteins...