One of the two archetypal pathways of caspase activation, known also as "the death receptor pathway." This pathway of programmed cell death is initiated through the stimulation of the transmembrane...Springer Berlin HeidelbergEncyclopedia of Cancer...
音频列表 1 albumin 732022-09 2 extrinsic pathway of apoptosis 782022-09 3 liquefaction necrosis 572022-09 4 apoptosis 482022-09 5 dystrophy calcification 402022-09 6 Mallory bodies 392022-09 7 lymphocyte 662022-09 8 mild autis 672022-09 9 47,XXY 702022-09 10 hyperuricemia 772022-09 查看更多...
The second pathway, which is also referred to as the‘intrinsic’pathway, is controlled by members of the Bcl-2 family. A long—stand 二条主要路为apoptosis启蒙存在。 一条路,也被命名`外在’路,由死亡感受器官, TNF感受器官的小群斡旋superfamily。 第二条路,也指`内在’路,由Bcl-2家庭的成员控制...
Apoptosis is known as a physiological process of cell deletion and is also a process of programmed cell death, resulting in morphological change and DNA fragmentation. It is stimulated by external or internal events of cells, one of which is the extrinsic pathway mediated by the death receptor. ...
Altered regulation of extrinsic apoptosis pathway in HCV-infected HCC cells enhances susceptibility to mapatumumab-induced apoptosis 喜欢 0 阅读量: 31 作者: X Zhang,AC Frank,CM Gille,M Daucher,J Kabat,S Becker,RA Lempicki,KJ Cortez,MA Polis,GM Subramanian 展开 摘要: Background: ...
A cell starts programmed cell death when DNA damage occurs, thereby activating the intrinsic pathway of apoptosis or when the extrinsic pathway is activated by external signals, such as the Fas ligand (FasL) or TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) (Wang, 2001). Effects...
The amino-terminal domain is responsible for this apoptotic activity, but surprisingly with no involvement of its transcriptional functions. The death pathway triggered by E2 relies on activation of the initiator caspase 8, specific of the extrinsic pathway of apoptosis. E2 itself is cleaved by ...
Furthermore, MMV560185 was found to specifically induce an extrinsic pathway of apoptosis in the parasitized cell. 2. Materials and methods 2.1. Chemicals Culture media RPMI-1640, Penicillin-Streptomycin, Dulbecco's Modified Eagle's Medium (DMEM), were purchased from Gibco, life technologies. Fetal...
Neddylation Inhibition Activates the Extrinsic Apoptosis Pathway through ATF4-CHOP-DR5 Axis in Human Esophageal Cancer Cells. Chen P, Hu T, Liang Y, Li P, Chen X, Zhang J, et al. Neddylation inhibition activates the extrinsic apoptosis pathway through ATF4- CHOP-DR5 axis in human esophageal ...
Moreover, apigenin reduced the tyrosine phosphorylation of HER2 (phospho- HER2 level) in MCF-7 HER2 cells, and up-regulated the levels of p53, phospho-p53 and p21 in MCF-7 vec and MCF-7 HER2 cells. This suggests that apigenin induces apoptosis through p53-dependent pathway. Apigenin also ...