Noxious stimuli (eg, physical, chemical, thermal) in peripheral tissues cause damage and the inflammatory response leads to the release of pain-producing substances that activate nociceptors on the terminals of sensory nerve fibers. This pain is the hallmark of protective response to adverse stimuli ...
Conversely, participants who had been sleeping, and thus unaware of getting noxious heat, displayed heightened pain during the first part of the test-phase. This heightened reaction to noxious stimuli—a pain alarm response—was further pronounced in the control conditions where participants were nave...
This kind of pain is time-limited and clears once the noxious stimuli are no longer present. There is a known cause of acute pain, and it is mainly attributed to trauma, medical diseases, or invasive procedures. This kind of pain is localized to the damaged area or that which is around...
Noxious stimuli (eg, physical, chemical, thermal) in peripheral tissues cause damage and the inflammatory response leads to the release of pain-producing substances that activate nociceptors on the terminals of sensory nerve fibers. This pain is the hallmark of protective response to adverse stimuli ...
Pain is a complex subjective feeling with sensory-discriminative (e.g. intensity, duration, localization of the noxious stimulus) and affective-motivational (e.g. unpleasantness) components. These different components are mapped in two partially separate nodes of a complex neural network referred to ...
controls by automated classification of cerebral fMRI activation patterns.This was achieved by applying a series of alternating noxious and innocuous tonic heat stimuli on the inner side of the left forearm to a group of female patients and gender and age matched healthy controls during fMRI ...