RonenMarmorstein,Mary X.Fitzgerald, inGene, 2003 Ets proteins contain a structurally conserved ETS DNA-binding domain that consists of a ‘winged helix–turn–helix’ topology. The ETS-domain mediates binding to DNA target sites harboring an invariant GGA core sequence (Sharrocks, 2001). Sequence...
Huang, CC., Papas, T. & Bhat, N. A variant form of ETS1 induces apoptosis in human colon cancer cells.15
(2006). ASK-1 (apoptosis signal-regulating kinase 1) is a direct E2F target gene. Biochem J 396: 547–556. Article CAS PubMed PubMed Central Google Scholar Kita D, Takino T, Nakada M, Takahashi T, Yamashita J, Sato H . (2001). Expression of dominant-negative form of Ets-1 ...
Correct vascular differentiation requires distinct patterns of gene expression in different subtypes of endothelial cells. Members of the ETS transcription factor family are essential for the transcriptional activation of arterial and angiogenesis-specific gene regulatory elements, leading to the hypothesis that...
This latter deletion mimics one of the alterations in the ets-1 gene transduced by the retrovirus E26 (30, 35). These studies led to a model of two inhibitory regions working together to sterically ...
Print datasheet MSDS ¥2200/100 μL Cat No.12280-1-AP 浓度:800 μg/ml 库存:现货 Size 发表文章 All (4) WB (3) IHC (1) Journal Impact FactorMost recent SpeciesApplicationTitle humanWB Cell Death Dis The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 acc...
Gene ID (NCBI) 2113 RRID AB_2881958 Conjugate Unconjugated Form Liquid Purification Method Protein A purification UNIPROT ID P14921 Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Storage Conditions Store at -20°C. Stable for one year after shipment. Aliquoting is unnecess...
Full Name v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) Calculated Molecular Weight 441 aa, 50 kDa Observed Molecular Weight 50 kDa GenBank Accession Number BC017314 Gene Symbol ETS1 Gene ID (NCBI) 2113 RRID AB_10664925 Conjugate Unconjugated Form Liquid Purification Method Antigen...
Full size image Ets1 function Numerous genes have been shown to respond to the transcription factor Ets1 [22]. However, whether a particular gene is indeed regulated by Ets1 or, alternatively, by a related Ets factor can often not be answered with certainty. To address this problem, Ets1-...
(F) AR reporter assay in COS7 cells transfected with AR, full length ETS1 and a short ETS1 isoform lacking the auto-regulatory domain, with androgen or vehicle treatment. AB Varambally, et al 2005 Tomlins, et al 2007 Supplementary Figure 3 Gene expression heatmaps and clustering of AR ...