estrogen-response,er网络雌激素受体 网络释义 1. 雌激素受体 ...dase ) 及 LacZ 报告基因於酵母细胞,经雌激素受体 (estrogen response, ER) 调控检测环境荷尔蒙 。pda.coa.gov.tw|基于7个网页© 2024 Microsoft 隐私声明和 Cookie 法律声明 广告 帮助 反馈...
网络雌激素效应元件;雌激素应答元件 网络释义
et al. (1986) Temporal and receptor correlates of the estrogen response in sheep. Am. J. Obstet. Gynecol., 154, 831-838.Greiss F.C., Rose J.C, Kute T.E, Kelly R.T., Winkler L.S., Temporal and receptor correlates of the estrogen response in sheep, Am. J. Obstet. Gynecol. ...
In conclusion, the estrogen response early score predicts response to endocrine therapy and is associated with survival in primary and metastatic breast cancer. 展开 关键词: ER GSEA GSVA biomarker endocrine estrogen response survival treatment response ...
Estrogenic effects are mediated through estrogen receptor (ER)α and ERβ, which, following the binding of estrogen, dimerize and activate estrogen response elements (EREs) in nuclear DNA. However, a fraction of total cellular ER is associated with the plasma membrane and mitochondria [2,3]. ...
Interaction of estrogen receptors α and β with estrogen response elements - ScienceDirect 来自 国家科技图书文献中心 喜欢 0 阅读量: 94 作者:Margaret,A.,Loven,and,Jennifer,R.,Wood,and,Ann,M.摘要: To understand how estrogen-responsive genes are regulated, we compared the abilities of estrogen ...
(NOER) mice. Interestingly, the role of mERα signaling for the estrogen response was highly tissue-dependent, with trabecular bone in the axial skeleton being strongly dependent (>80% reduction in estrogen response in NOER mice), cortical and trabecular bone in long bones, as well as uterus ...
Estrogen response is mainly mediated by the nuclear receptor family of transcription factors, estrogen receptor α (ERα) and estrogen receptor β (ERβ)18,19and the newly described G protein-coupled estrogen receptor 120. Estrogen-bound ERs translocate to the nucleus, where they increase transcript...
After binding to estrogen, the receptors associate with specific estrogen response elements (EREs) within the promoters of estrogen-regulated genes or the receptors affect the activity of other transcription factor complexes such as AP- 1 (Jun–Fos). The two ER subtypes share affinity for the DCC...
To determine whether accessory proteins mediate the ligand- and DNA sequence-dependent specificity of estrogen receptor (ER) interaction with DNA, the binding of partly purified vs highly purified bovine ER to various estrogen response elements (EREs) was measured in the presence of different ER liga...