In conclusion, the estrogen response early score predicts response to endocrine therapy and is associated with survival in primary and metastatic breast cancer. 展开 关键词: ER GSEA GSVA biomarker endocrine estrogen response survival treatment response ...
Estrogen receptors status and response to chemotherapy in early and advanced breast cancer. Cancer Chemocher Phannacal 1980; 4:37-41.Bonadonna G, Valagussa P, Tancini G, Di Fronzo G. Estrogen-receptor status and response to chemotherapy in early and advanced breast cancer. Cancer Chemother ...
The "developmental origin of health and disease" (DOHaD) theory posits that the health of an individual is closely related to their health status early in life5. Current research on the fetal origin of adult diseases is now more extensive and in-depth, and an increasing number of adverse ...
CONTEXT: The Women's Health Initiative (WHI) trial of estrogen plus progestin was stopped early because of adverse effects, including an increased risk of ... S Wassertheil-Smoller,SL Hendrix,M Limacher,... - 《Jama》 被引量: 4169发表: 2003年 Protective effects of estrogen on the cardiova...
The significance of the difference between E2B-treated and control group is greater(p < 0.0001) at the early time points(day 5 and 8) than that at the later time points(day 12 and 14)(p < 0.01). It is possible that the effect of E2B is boasted by the inflammatory condition...
In the late 1970s and early 1980s, the role of chemotherapy was extended to preoperative and postoperative adjuvants, radiosensitizers to enhance radiation effects, and supportive therapy to increase the tolerance of the organism toward toxicity.26 We have progressed in a few years from a lack ...
Temporal and spatial alterations in uterine estrogen receptor and progesterone receptor gene expression during the estrous cycle and early pregnancy in the... Mechanisms regulating responses of the ovine uterus to endocrine and paracrine signals during the estrous cycle and pregnancy are likely to ...
Early pregnancy detection in dairy cattle is an integral part of a successful animal husbandry practice. A simple seed germination technique (Punyakoti test) comprises observation of differential seed germination response of wheat seeds to diluted fresh urine samples as reflected by significant inhibition...
et al. A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells. Cell 145, 622–34 (2011). 45. Jagannathan, V. & Robinson-Rechavi, M. Meta-analysis of estrogen response in MCF-7 distinguishes early target genes involved in signaling and cell ...
Cumulatively, our data suggest that, ERα-KO strongly affected the early autophagic initiation and altered the LC3 nuclear-cytoplasmic translocation, thereby influencing the sex-biased final autophagosome formation in medaka. Thus, existence of steroid responsive autophagy regulatory-switches and sex-biased...