Kwasniewska A, Postawski K, Gozdzicka-Jozefiak A, Kwasniewski W, Grywalska E, Zdunek M, et al. Estrogen and progesterone receptor expression in HPV-positive and HPV-negative cervical carcino- mas. Oncol Rep. 2011; 26(1):8. Epub 2011 Apr 12....
Other than for breast cancer, endocrine therapy has not been highly effective for gynecologic cancers. Endocrine therapy resistance in estrogen receptor positive gynecologic cancers is still poorly understood. In this retrospective study, we examined the
The human uterine endometrial cancer cell line HEC-1A and the telomerase-transformed human endometrial stromal cells T-HESCs were purchased from the American Type Culture Collection (Manassas, VA, USA). Ishikawa and HEC-1A cells were maintained in Minimum Essential Medium (MEM) (Nacalai Tesque, ...
Recently, it has been suggested that vascular endothelial growth factor (VEGF) could be one of the transcriptional targets of ERRα in breast cancer. Here, we examined the expression of ERRα and the association of ERRα with VEGF in uterine cervical cancer cells and tissues.We evaluated the ...
DR Ciocca,LA Puy,LC Fasoli - 《Cancer Research》 被引量: 110发表: 1989年 Cellular turnover in the rat uterine cervix and its relationship to estrogen and progesterone receptor dynamics. Bosquiazzo VL, Luque EH & Munoz-de-Toro M 2002 Cellular turnover in the rat uterine cervix and its ...
Due to their role in cell proliferation, estrogen receptors can also increase the risk of breast cancer and uterine cancer. If cells in the breasts or uterine lining have begun to mutate due to environmental or genetic causes, the estrogen receptor can cause the mutated cells to proliferate. Th...
The estrogen receptor (ER) is the single most powerful predictor of breast cancer prognosis as well as an important contributor to the biology of carcinogenesis. In addition, endocrine therapy targeting ER directly (SERMS) or indirectly (aromatase inhibitors) forms the mainstay of adjuant therapy....
It is a synthetic estrogen that binds with high affinity to estrogen receptors and in daughters exposed in utero, it caused cervical cancer, uterine malformations, cardiovascular issues, endometriosis, and an increased likelihood of developing breast cancer. ...
et al. Estrogen-related receptor-gamma regulates estrogen receptor-alpha responsiveness in uterine endometrial cancer. Int. J. Gynecol. Cancer 22, 1509–1516 (2012). PubMed Google Scholar Yu, S., Wang, X., Ng, C. F., Chen, S. & Chan, F. L. ERRgamma suppresses cell proliferation ...
Korach2 Aberrant regulation of uterine cell growth can lead to endometrial cancer and infertility. To understand the molecular mechanisms of estrogen-induced uterine cell growth, we removed the estrogen receptor α (Esr1) from mouse uterine stromal cells, where the embryo is implanted during pregnancy...