Estrogen receptor-positivebreast cancer:amultidisciplinary challenge. Zwart W,Theodorou V,Carroll JS. Wiley Inter-discip Rev Syst Biol Med . 2011Zwart W., Theodorou V., Carroll J. S. (2011). Estrogen receptor-positive breast cancer: a multidisciplinary challenge . Wiley Interdiscip. Rev. Syst. ...
Estrogen receptor-positive breast cancer: a multidisciplinary challenge. Wiley Interdiscip Rev Syst Biol Med 2011; 3: 216-230.Zwart, W.; Theodorou, V.; Carroll, J.S. Estrogen receptor-positive breast cancer: A multidisciplinary challenge. Wiley Interdiscip Rev. Syst. Biol. Med. 2011, 3, 216...
Estrogen Receptor-Positive Breast Cancer: Traditional Prognostics, Molecular Pathology: A New Breast Cancer Taxonomy and 21st Century Personalized Prognostic and Predictive AssaysEstrogen Receptor-Positive Breast Cancer: Traditional Prognostics, Molecular Pathology: A New Breast Cancer Taxonomy and 21st Century...
Theestrogen receptor(ER) is an important driver in the proliferation, tumorigenesis, and progression of breast cancers, and targeting ER signaling at different levels is a successful strategy in the control ofhormone receptorpositive (HR+) breast cancer.Endocrine therapyhas been the treatment of choic...
An experimental drug rapidly shrinks most tumors in a mouse model of human breast cancer, researchers report in the Proceedings of the National Academy of Sciences. When mice were treated with the experimental drug, BHPI, "the tumors immediately stopped
Mislabeled Figures:In the Original Contribution entitled “Estrogen-Receptor Status and Outcomes of Modern Chemotherapy for Patients With Node-Positive Breast Cancer” published in the April 12, 2006, issue ofJAMA(2006;295:1658-1667), incorrect titles and legends were matched with the figures. The ...
Estrogen receptor (ER)-positive breast cancer, including luminal-A and -B, is the most common type of breast cancer. Extended exposure to estrogen is associated with an increased risk of breast cancer. Both ER-dependent and ER-independent mechanisms have been implicated in estrogen-mediated carcin...
Estrogen receptor (ER) expression is the main indicator of potential responses to endocrine therapy (ET), and approximately 70% of human breast cancers (BCs) are hormone-dependent and ER-positive. The introduction of adjuvant systemic therapy led to a significant improvement in post-surgical surviva...
npj Breast CancerLumachi F, Brunello A, Maruzzo M, Treatment of estrogen receptor-positive breast cancer. Curr Med Chem. 2013 ;20(5):596–604.Lumachi F, Brunello A, Maruzzo M, Basso U, Basso SM. Treatment of estrogen receptor-positive breast cancer. Curr Med Chem. 2013; 20 (5):...
The role of the androgen receptor (AR) in estrogen receptor (ER)-α-positive breast cancer is controversial, constraining implementation of AR-directed therapies. Using a diverse, clinically relevant panel of cell-line and patient-derived models, we demonstrate that AR activation, not suppression, ...