Escherichia coli Nissle1917(EcN)肠炎肿瘤大肠埃希菌Nissle1917,简称EcN,是益生菌中为数不多的革兰氏阴性菌,在临床上主要用于克罗恩病,溃疡性结肠炎等胃肠功能障碍.其机制在于EcN能在人体肠道定殖,并阻止病原菌对肠道黏膜的侵袭,对肠道黏膜屏障具有保护和修护作用.EcN还参与机体的免疫调控,平衡免疫因子的分泌,增强...
口服益生菌Escherichia coli Nissle 1917调控断奶仔猪空肠黏膜屏障功能的机理研究 旨在探讨口服益生菌Escherichia coli(E.coli)Nissle 1917调控病原菌E.coli Abbottstown攻毒或未攻毒21d断奶仔猪肠道屏障功能的机理。将20头21d断奶仔猪((6.35±0.38)k... 唐志如,邓欢,孙卫忠,... - 《畜牧兽医学报》 被引量: 4发表...
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Escherichia coli Nissle 1917 (Mutaflor): new insights into an old probiotic bacterium. Escherichia coli Nissle 1917 (Mutaflor): new insights into an old probiotic bacterium. Dig Dis 2011; 29: 600-607 [PMID: 22179217 DOI: 10.1159/000333307... Christoph,A,Jacobi,... - 《Digestive Diseases》 ...
E.coliNissle1917(EcN)是一个可用的改造宿主.在一个世纪前,它就被用于治疗炎症性肠病和肠易激综合征.由于其安全特性和遗传可塑性,用它作为载体构建的工程菌被用作治疗多种疾病,如细菌感染,代谢紊乱等.最近,通过静脉注射,EcN能够作为向肿瘤部位递送抗癌药物的载体,这进一步证明EcN对人体具有较低的免疫原性,相对...
edu. cn 收稿日期:2018~08~20抗肿瘤工程菌 EscherichiacoliNissle1917发酵培养基优化及微胶囊制备吴柳娟ꎬ 李 躺ꎬ 莫相涛ꎬ 胡益波ꎬ 丁学知ꎬ 夏立秋 ∗(湖南师范大学 生命科学学院ꎬ湖南 长沙 410081)摘 要 为了获得高活力抗肿瘤工程菌 EscherichiacoliNissle1917(EcNA)微胶囊制剂ꎬ对 EcNA 进行...
Escherichia coli Nissle 1917 (EcN) has become a research hotspot in inflammatory bowel disease (IBD). It has a strong targeting effect on the colon, and has some therapeutic effect on inflammatory bowel disease . EcN is prepared into EcN ghosts, which also retain EcN's biological characteristics...
大肠杆菌属Nissle 1917研究进展Research progress on Escherichia coli strain Nissle 1917 大肠杆菌属Nissle 1917(EcN)是目前广泛应用的一种益生菌。研究发现EcN对常见胃肠道疾病有良好疗效,被广泛用于预防传染性腹泻、溃疡性结肠炎等炎性肠疾病,防止新生儿消... 陈祥娥 - 《中国生化药物杂志》 被引量: 0发表: 0...
We evaluated the capacity for supernatants (SNs) derived from Escherichia coli Nissle 1917 (EcN), cultured under different growth conditions, to prevent 5-fluorouracil (5-FU)-induced intestinal epithelial cell damage. EcN was cultured in: Luria Bertani (LB) broth, tryptone soya broth (TSB), de...
Probiotics, such as Escherichia coli Nissle 1917 (EcN), have been shown to be beneficial for prevention and treatment of several chronic inflammatory diseases.Objective: The aim of this study was to investigate the impact of oral EcN administration on development and outcome of allergen-induced ...