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ZebrafishDrug delivery systemEscherichia coli Nissle 1917 (EcN) has become a research hotspot in inflammatory bowel disease (IBD). It has a strong targeting effect on the colon, and has some therapeutic effect on inflammatory bowel disease. EcN is prepared into EcN ghosts, which also retain EcN...
Escherichia coli Nissle 1917 (EcN) is a Gram-negative bacterium that is used to treat inflammatory bowel diseases. The probiotic character of EcN is not well-understood, but its ability to produce secondary metabolites plays an important role in its activity. The EcN genome encodes for an aryl...
Physiologically Inspired Mucin Coated Escherichia coli Nissle 1917 Enhances Biotherapy by Regulating the Pathological Microenvironment to Improve Intestinal Colonization 生理启发粘蛋白包被大肠杆菌Nissle 1917通过调节病理微环境改善肠道定植来增强生物治疗 相关...
Escherichia coli Nissle 1917 (Mutaflor) is one of the most investigated probiotic bacteria. While the number of reports discussing the underlying mechanisms of Mutaflor has increased rapidly in recent years, novel clinical studies are missing. Here we provide an overview of the mechanisms of action ...
The HIV-1 MPER epitope was successfully introduced in the porin OmpF of theE. coliNissle 1917 (EcN-MPER) and the modification was stable over 30 passages of the recombinant bacteria on the DNA and protein level. Furthermore, the introduced epitope was recognized by a human anti-HIV-1 gp41...
Probiotics, such as Escherichia coli Nissle 1917 (EcN), have been shown to be beneficial for prevention and treatment of several chronic inflammatory diseases.Objective: The aim of this study was to investigate the impact of oral EcN administration on development and outcome of allergen-induced ...
Escherichia coli is the most well-studied model prokaryote and has become an indispensable host for the biotechnological production of proteins and biochemicals. In particular, the probiotic status of one E. coli strain, E. coli Nissle 1917 (EcN) has helped it become a new favorite amongst synth...
E.coli K5合成Heparosan关键酶基因kfic的克隆与表达及Heparosan解聚 coli K5克隆到了产heparosan关键酶基因kfic,并将测序结果于NCBI上进行BLAST比对,获得的KfiC基因与Escherichia coli Genomic Island II, strain Nissle1917的同源性为... 严子琴 - 《浙江工业大学》 被引量: 2发表: 2012年 Engineering the ...
Escherichia coli Nissle 1917 (EcN) is one of the most widely used probiotics to treat gastrointestinal diseases. Recently, many studies have engineered EcN to release therapeutic proteins to treat specific diseases. However, because EcN exhibits intestinal metabolic activities, it is difficult to ...