clindamycinerythromycinGroup B streptococcusBackground: Intrapartum chemoprophylaxis for group B streptococcus (GBS) carriers reduces the risk of early-onset neonatal GBS infection. For women with β-lactam allergy, either erythromycin or clindamycin are administered. Recent reports worldwide suggest that ...
Mutations in genes for 50S ribosomal proteins or bases of critical domains of the 23S rRNA receptor site confer resistance to erythromycin and sometimes to other macrolides, lincomycin, and clindamycin; in some but not all strains, this is associated with a decreased binding affinity for erythromycin...
Erythromycinis a macrolide and like clindamycin has bacteriostatic features. It is available in gel, solution, and ointment in 2% concentration. The administration of erythromycin due to the higher rate of bacterial resistance has been limited [31,45]. View article Aspiration Prevention and Prophylaxis...
Objective: To determine both the frequency of reported penicillin allergy in parturients and the frequency of resistance in vitro of clinical isolates of group B streptococci to clindamycin and erythromycin. Methods: One hundred clinical isolates of group B streptococci were tested to determine the ...
Objective: To determine both the frequency of reported penicillin allergy in parturients and the frequency of resistance in vitro of clinical isolates of group B streptococci to clindamycin and erythromycin. Methods: One hundred clinical isolates of group B streptococci were tested to determine the ...