Clindamycin in recurrent group A streptococcal pharyngotonsillitis--an alternative to tonsillectomy? Orrling A, Stjernquist-Desatnik A, Schalen C: Clindamycin in recurrent group A streptococcal pharyngotonsillitis--an alternative to tonsillectomy? Acta ... A Orrling,A Stjernquist-Desatnik,C Schalen ...
Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore, it should be used with caution in patients receiving such agents. Antagonism has been demonstrated between clindamycin and erythromycin in vitro. Because of ...
Resistance to clindamycin is often associated with resistance to erythromycin. 13. Nonclinical Toxicology 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility The carcinogenicity of a 1.2% clindamycin phosphate gel similar to clindamycin phosphate foam was evaluated by daily topical administration to mice...
14 Resistance to clindamycin may develop, and is generally the result of base modification within the 23S ribosomal RNA. Cross-resistance between clindamycin and lincomycin is complete, and may also occur between clindamycin and macrolide antibiotics (e.g. erythromycin) due to similarities in their ...
faecalis and Neisseria gonorrhoeae.Clinical trials seem to be justified in infections with sensitive organisms for which erythromycin might have been indicated. 展开 关键词: antibiotics bacterial diseases clindamycin derivatives erythromycin human diseases in vitro infections lincomycin penicillins ...
314 Third, alteration in particular 50S ribosomal proteins of the receptor site confers resistance to erythromycin and often to the lincosamides1; this mechanism was previously discussed for erythromycin. Fourth, resistance is conferred through inactivation of lincomycin and clindamycin by a few isolates...
If you have recently taken or used other clindamycin or erythromycin-containing medicines, there is an increased chance that CLINDETS®will not work as well as it should. BEFORE you use CLINDETS®talk to your doctor or pharmacist if you: ...
erythromycin(taken by mouth or applied to the skin). This list is not complete. Other drugs may affect clindamycin topical, including prescription and over-the-counter medicines,vitamins, andherbal products. Not all possibledrug interactionsare listed here. ...
Although chemically dissimilar to erythromycin and the macrolide antibiotics, in vitro antagonism occurs as a result of a similar site of binding and mechanism of action. In addition, topical clindamycin can reduce the free fatty acid concentrations on the skin and further suppresses the growth of ...
Related to clindamycin:metronidazole,Clindamycin phosphate clin·da·my·cin (klĭn′də-mī′sĭn) n. A semisynthetic antibiotic, C18H33ClN2O5S, derived from lincomycin and active against gram-positive bacteria. [Alteration and blend ofchloro-andlincomycin(withdperhaps fromdeoxy-).] ...