The epithelial-mesenchymal transition (EMT) is a multi-step morphogenetic process in which epithelial cells lose their epithelial properties and gain mesenchymal characteristics. The process of EMT has been shown to mediate mammary gland fibrosis. Understanding how mesenchymal cells emerge fro...
Epithelial-mesenchymal transition GBM: Glioblastoma TUBB2B: Tubulin beta 2B class IIb IF: Immunofluorescence Co-IP: Co-immunoprecipitation shRNA: Short hairpin RNA OERNA: Overexpression RNA MutRNA: Mutant RNA IHC: Immunohistochemistry PBS: Phosphate-buffered saline DAB: Diaminobenzidine ...
an epithelial-mesenchymal transition associated gene resource Min Zhao1,*, Lei Kong2,*, Yining Liu1,* & Hong Qu2 As a cellular process that changes epithelial cells to mesenchymal cells, Epithelial-mesenchymal transition (EMT) plays important roles in development and cancer metastasis. ...
Epithelial-mesenchymal transition (EMT) is designated as one of the prime causes of chemoresistance in many cancers. In our previous study we established that cisplatin resistance in ovarian cancer (OC) is associated with EMT using sensitive OV90 cells and its resistant counterparts OV90CisR1 and ...
[72] demonstrated elevated MPP7 expression in breast cancer patients compared to healthy individuals, with MPP7 promoting cancer cell metastasis by regulating epithelial-mesenchymal transition (EMT) and activating EGFR/AKT signaling. Intriguingly, our RNA-seq results reveal a significant upregulation of ...
Epithelial–mesenchymal transition CIN: Cervical intraepithelial neoplasia LSD: Least significant difference ANOVA: One-way analyses of variance GO: Gene ontology DVL1: Dishevelled Segment Polarity Protein 1 TCF7: Transcription factor 7 KRT17: Keratin 17 VMAC: Vimentin gene GSK3β: Glycoge...
Epithelial-mesenchymal transition EMT-TFs: EMT-related transcription factors F. nucleatum: Fusobacterium nucleatum KEGG: Kyoto encyclopedia of genes and genomes LDA: Linear discriminant analysis scores MUT: Mutated TCGA: The cancer genome Atlas qRT-PCR: Quantitative reverse transcription polymerase...
Epithelial-mesenchymal transition EMT-TFs: EMT-related transcription factors F. nucleatum: Fusobacterium nucleatum KEGG: Kyoto encyclopedia of genes and genomes LDA: Linear discriminant analysis scores MUT: Mutated TCGA: The cancer genome Atlas qRT-PCR: Quantitative reverse transcription polymerase...
Epithelal-mesenchymal transition Fap2: Fibroblast activation protein 2 F.n: Fusobacterium nucleatum F.p: Fusobacterium periodonticum GLUT1: Glucose transporter 1 GPR81: G protein-coupled receptor 8 HIF-1α: Hypoxia Inducible Factor 1 Subunit Alpha HK2: Hexokinase 2 LA: Lactic acid ...
Long noncoding RNAs play an important role in several pathogenic processes in diabetic nephropathy, but the relationship with epithelial-mesenchymal transition in DN is unclear. Herein, we found that KIFAP3-5:1 expression was significantly down-regulated in DN plasma samples, db/db mouse kidney tis...