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Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells..Suming ...
Regulation of gene expression by N6-methyladenosine in cancer. Trends Cell Biol. 29, 487–499 (2019). PubMed PubMed Central Google Scholar Delaunay, S. & Frye, M. RNA modifications regulating cell fate in cancer. Nat. Cell Biol. 21, 552–559 (2019). CAS PubMed Google Scholar Neb...
Cells of a multicellular organism are genetically homogeneous but structurally and functionally heterogeneous owing to the differential expression of genes. Many of these differences in gene expression arise during development and are subsequently retain
We observed that meQTL were more stable between tissues than eQTL and a very strong tissue-specificity for the identified associations between CpG methylation and gene expression. Conclusions Our analyses generated a comprehensive resource of factors involved in the regulation of hepatic gene expression,...
Calicchio R, Doridot L, Miralles F, Mehats C, Vaiman D1. DNA methylation, an epigenetic mode of gene expression regulation in reproductive science. Curr Pharm Des. 2014; 20(11):1726-1750.Calicchio R, Doridot L, Miralles F et al (2014) DNA methyla- tion, an epigenetic mode of ...
To understand the changes of gene regulation in carcinogenesis, we explored signals of DNA methylation – a stable epigenetic mark of gene regulatory elements — and designed a computational model to profile loss and gain of regulatory elements (REs) during carcinogenesis. We also utilized sequencing...
Epigenetic regulation of gene expression in Chinese Hamster Ovary cells in response to the changing environment of a batch culture The existence of dynamic cellular phenotypes in changing environmental conditions is of major interest for cell biologists who aim to understand the mechan... I Hernandez,...
2012. Genetic and epigenetic regulation of Tcrb gene assembly. Curr Top Microbiol Immunol 356:91-116. http://dx.doi.org/10 .1007/82_2011_138.Sikes,M.L. and Oltz,E.M. (2012) Genetic and epigenetic regulation of Tcrb gene assembly. Curr. Top. Microbiol. Immunol., 356, 91-116....
lincRNA的基因调节--GeneticandEpigeneticRegulationofHumanlincRNAGeneExpression 系统标签: lincrnaexpressionepigeneticgenelincrnasregulation ARTICLEGeneticandEpigeneticRegulationofHumanlincRNAGeneExpressionKonstantinPopadin,1,2,3,6MariaGutierrez-Arcelus,1,2,4,6EmmanouilT.Dermitzakis,1,2,4,5,*andStylianosE.Anto...