Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells..Suming ...
【分生笔记】基因表达的表观遗传调控—Epigenetic regulation of gene expression 仅作为分享及交流使用,部分图片来源于教材及图库。 如果觉得有用的话请给个三连。 严禁转载。
Studies of mammalian gene function are hampered by temporal limitations in which phenotypes occurring at one stage of development interfere with analysis at later stages. Moreover, phenotypes resulting from altered gene activity include both direct and indirect effects that may be difficult to distinguis...
R. et al. A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling. Cell 138, 114–128 (2009). Article CAS PubMed PubMed Central Google Scholar Hargreaves, D. C., Horng, T. & Medzhitov, R. Control of inducible gene expression by ...
We observed that meQTL were more stable between tissues than eQTL and a very strong tissue-specificity for the identified associations between CpG methylation and gene expression. Conclusions Our analyses generated a comprehensive resource of factors involved in the regulation of hepatic gene expression,...
Epigenetic regulation of gene expression in Chinese Hamster Ovary cells in response to the changing environment of a batch culture The existence of dynamic cellular phenotypes in changing environmental conditions is of major interest for cell biologists who aim to understand the mechan... I Hernandez,...
1、朱冰2015年华中科技大学贝时璋班中科院生物物理所表观遗传学EpigeneticsEpigenetics: From Phenomenon to FieldPosition effect variegation (PEV)Elgin and Reuter (2006) in EpigeneticsGene neighborhood matters for gene expression!Observed on 1930 by Muller! Hermann Muller1946 Nobel Prize LaurateTelomeric position...
Although the concept of epigenetic regulation of gene expression is over 70 years old, the field of epigenetics has recently exploded, with 98% of epigenetic research published in the last 15 years[26]. Many CNS functions have significant epigenetic components, includingneural stem cellfate determina...
lincRNA的基因调节--GeneticandEpigeneticRegulationofHumanlincRNAGeneExpression 系统标签: lincrnaexpressionepigeneticgenelincrnasregulation ARTICLEGeneticandEpigeneticRegulationofHumanlincRNAGeneExpressionKonstantinPopadin,1,2,3,6MariaGutierrez-Arcelus,1,2,4,6EmmanouilT.Dermitzakis,1,2,4,5,*andStylianosE.Anto...
Cells of a multicellular organism are genetically homogeneous but structurally and functionally heterogeneous owing to the differential expression of genes. Many of these differences in gene expression arise during development and are subsequently retain