The stratum compactum and stratum spongialis develop into the stratum functionalis (functional layer) during the proliferative phase of the menstrual cycle. The appearance of the endometrium on ultrasound varies in a relatively characteristic pattern throughout the cycle. The endometrium is relatively ...
Using scRNAseq on endometrial biopsies in the proliferative stage (between the menstrual and secretory stage), Queckbörner et al. identified multiple stromal populations suggestive of specific stromal niches with the ability to regulate inflammation and ECM composition. They further characterized vascular...
During the proliferative phase, immunostaining intensity of Brx was greater in both the glandular and the stromal compartments of biopsies from patients with endometriosis compared to healthy volunteers; nuclear stromal Brx staining was more common in patients with endometriosis. Conclusion(s) The spatio...
The endometrium undergoes regular regeneration and stromal proliferation as part of the normal menstrual cycle. To better understand cellular interactions driving the mechanisms in endometrial regeneration we employed single-cell RNA sequencing. Endometrial biopsies were obtained during the proliferative phase ...