The interaction between CIS and the Elongin B/C complex, which depends on the levels of uncomplexed Elongin B/C, was easily disrupted. This regulatory mechanism may be unique for CIS, as similar mutations in SOCS1, -2, -3, -6, and -7 had no functional impact. Our findings indicate ...
Elongin B is a protein that forms a complex with other proteins like VHL and elongin C, playing a role in protein degradation by catalyzing ubiquitin chain assembly. AI generated definition based on: Learning and Memory: A Comprehensive Reference, 2008 ...
VHL is bound to a heterodimer complex composed of Elongin B (ELOB) and Elongin C (ELOC) through the "BC-box motif" found in many proteins in the VHL-box and SOCS-box protein families. ELOB/ELOC serves as an adapter between substrate recognition proteins and Cullin-2 (or Cullin-5) ...
ChemicalBook provide Chemical industry users with Recombinant Human Elongin B/Elongin C/VHL Complex, CF Boiling point Melting point,Recombinant Human Elongin B/Elongin C/VHL Complex, CF Density MSDS Formula Use,If You also need to Recombinant Human Elong
Storage Conditions Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 背景介绍 TCEB2 encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex and is also reported to function as an adapter protein in the...
The VHL gene product (pVHL) forms a multimeric complex with the elongin B and C, Cul2 and Rbx1 proteins (VCBCR complex), which is homologous to the SCF family of ubiquitin ligase complexes. The VCBCR complex binds HIF-1α and HIF-2α, transcription factors critically involved in cellular...
Storage Conditions Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. Background Information TCEB2 encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex and is also reported...
英文别名: Recombinant Human Elongin B/Elongin C/VHL Complex, CF中文名: 中文别名: CBNumber: CB115325551 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 Recombinant Human Elongin B/Elongin C/VHL Complex, CF化学性质 ...
b,c, Overview of the Pol II–SPT6–Elongin structure (structure 1): front view (b) and back view (c). Pol II is shown as surface presentation. ELOA, ELOB, ELOC and SPT6 are shown as cartoon presentation. Pol II, ELOA, ELOB, ELOC, SPT6, template DNA, nontemplate DNA and RNA ...
Pol 11, RNA polymerase 11; A, elongin A; B, elongin B; C, elongin C; mRNA, messenger RNA. The elongin BC complex has recently been shown to be a potential target for regulation by the product of the von Hippel–Lindau (VHL) tumor suppressor gene (157, 158). The VHL gene is ...